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Coexpression cluster:C3628

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Full id: C3628_caudate_putamen_Pericytes_diencephalon_cerebral_thalamus_ductus



Phase1 CAGE Peaks

Hg19::chr17:37783139..37783148,+p6@PPP1R1B
Hg19::chr17:37783170..37783182,+p2@PPP1R1B
Hg19::chr17:37783186..37783195,+p5@PPP1R1B


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism1.82e-63114
neural tube3.20e-5856
neural rod3.20e-5856
future spinal cord3.20e-5856
neural keel3.20e-5856
central nervous system3.03e-5681
regional part of nervous system7.72e-5553
regional part of brain7.72e-5553
brain7.92e-5468
future brain7.92e-5468
nervous system2.98e-5089
neural plate1.90e-4982
presumptive neural plate1.90e-4982
neurectoderm4.67e-4986
regional part of forebrain5.41e-4241
forebrain5.41e-4241
anterior neural tube5.41e-4241
future forebrain5.41e-4241
ecto-epithelium5.78e-37104
pre-chordal neural plate4.18e-3661
telencephalon6.60e-3534
brain grey matter1.04e-3434
gray matter1.04e-3434
cerebral hemisphere1.21e-3232
regional part of telencephalon1.29e-3232
ectoderm-derived structure2.40e-32171
ectoderm2.40e-32171
presumptive ectoderm2.40e-32171
structure with developmental contribution from neural crest2.34e-28132
regional part of cerebral cortex6.38e-2822
organ system subdivision6.71e-28223
neocortex1.37e-2520
cerebral cortex1.08e-2325
pallium1.08e-2325
posterior neural tube9.42e-1715
chordal neural plate9.42e-1715
anatomical cluster5.83e-15373
segmental subdivision of nervous system9.59e-1513
segmental subdivision of hindbrain1.24e-1312
hindbrain1.24e-1312
presumptive hindbrain1.24e-1312
basal ganglion7.25e-139
nuclear complex of neuraxis7.25e-139
aggregate regional part of brain7.25e-139
collection of basal ganglia7.25e-139
cerebral subcortex7.25e-139
neural nucleus1.38e-129
nucleus of brain1.38e-129
multi-tissue structure1.32e-11342
organ1.14e-10503
telencephalic nucleus1.36e-107
regional part of metencephalon6.01e-109
metencephalon6.01e-109
future metencephalon6.01e-109
temporal lobe1.41e-096
tube1.72e-09192
anatomical conduit3.19e-09240
organ part3.45e-09218
embryo7.09e-09592
gyrus1.08e-086
diencephalon2.21e-087
future diencephalon2.21e-087
brainstem2.39e-086
limbic system1.48e-075
multi-cellular organism1.69e-07656
occipital lobe1.96e-075
embryonic structure4.05e-07564
corpus striatum4.48e-074
striatum4.48e-074
ventral part of telencephalon4.48e-074
future corpus striatum4.48e-074
parietal lobe4.91e-075
germ layer5.30e-07560
germ layer / neural crest5.30e-07560
embryonic tissue5.30e-07560
presumptive structure5.30e-07560
germ layer / neural crest derived structure5.30e-07560
epiblast (generic)5.30e-07560
cerebellum6.00e-076
rhombic lip6.00e-076
developing anatomical structure6.25e-07581


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.0471418
MA0004.10.826076
MA0006.11.5435
MA0007.10.804807
MA0009.11.3275
MA0014.12.44638
MA0017.10.686276
MA0019.10.990656
MA0024.11.21731
MA0025.11.46617
MA0027.12.95767
MA0028.10.658629
MA0029.11.23771
MA0030.11.22561
MA0031.11.15713
MA0038.10.94098
MA0040.11.24388
MA0041.10.847069
MA0042.10.810843
MA0043.11.32783
MA0046.11.31611
MA0048.10.341392
MA0050.10.81185
MA0051.10.936307
MA0052.11.24796
MA0055.10.557638
MA0056.10
MA0057.12.4146
MA0058.10.716037
MA0059.10.714521
MA0060.12.13518
MA0061.10.456531
MA0063.10
MA0066.10.941452
MA0067.11.65513
MA0068.10.405474
MA0069.11.31207
MA0070.11.30033
MA0071.10.897953
MA0072.11.29561
MA0073.11.36698
MA0074.10.935474
MA0076.10.734647
MA0077.11.28751
MA0078.11.04495
MA0081.10.714712
MA0083.11.33535
MA0084.11.84562
MA0087.11.29304
MA0088.10.257905
MA0089.10
MA0090.10.751469
MA0091.10.829044
MA0092.10.785956
MA0093.10.642957
MA0095.10
MA0098.10
MA0100.10.956299
MA0101.10.646932
MA0103.10.628063
MA0105.14.18141
MA0106.10.986396
MA0107.10.556367
MA0108.21.15387
MA0109.10
MA0111.11.80901
MA0113.11.00436
MA0114.10.549955
MA0115.11.57693
MA0116.13.4624
MA0117.11.36676
MA0119.10.695578
MA0122.11.39371
MA0124.11.53432
MA0125.11.44766
MA0130.10
MA0131.11.06461
MA0132.10
MA0133.10
MA0135.11.35921
MA0136.10.948776
MA0139.10.440097
MA0140.10.894983
MA0141.10.712476
MA0142.11.12317
MA0143.11.00455
MA0144.10.531867
MA0145.11.37817
MA0146.11.70974
MA0147.11.38767
MA0148.10.854239
MA0149.10.884158
MA0062.20.449458
MA0035.20.894194
MA0039.20.0526989
MA0138.21.04628
MA0002.20.476938
MA0137.20.666381
MA0104.20.491226
MA0047.20.973066
MA0112.20.264678
MA0065.20.760954
MA0150.10.744617
MA0151.10
MA0152.10.902317
MA0153.11.43021
MA0154.10.838867
MA0155.10.256269
MA0156.10.669101
MA0157.11.09377
MA0158.10
MA0159.11.38935
MA0160.10.871361
MA0161.10
MA0162.10.149099
MA0163.14.77883
MA0164.11.01792
MA0080.20.643061
MA0018.20.987913
MA0099.20.902716
MA0079.28.812
MA0102.21.88331
MA0258.10.519674
MA0259.10.575594
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.