Coexpression cluster:C16: Difference between revisions
From FANTOM5_SSTAR
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{ | |||
Latest revision as of 10:07, 17 September 2013
Full id: C16_medial_amygdala_occipital_parietal_olfactory_putamen_brain
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| p.value | FDR | nGenes | nPathway | Name |
|---|---|---|---|---|
| 3.69014875770592e-06 | 0.000233586416362785 | 6 | 87 | ErbB signaling pathway (KEGG):04012 |
| 2.22288165848138e-05 | 0.000879427556136695 | 7 | 177 | Calcium signaling pathway (KEGG):04020 |
| 4.78305071489987e-05 | 0.00168203950140646 | 8 | 272 | Neuroactive ligand-receptor interaction (KEGG):04080 |
| 0.00213598548460053 | 0.0386308231929181 | 4 | 114 | Oocyte meiosis (KEGG):04114 |
| 0.0022754369354268 | 0.0400097661145878 | 4 | 116 | Vascular smooth muscle contraction (KEGG):04270 |
| 1.02323169514755e-06 | 9.25293804326286e-05 | 6 | 70 | Long-term potentiation (KEGG):04720 |
| 3.23698050961303e-05 | 0.00120529921328532 | 6 | 127 | Neurotrophin signaling pathway (KEGG):04722 |
| 2.24009401753453e-11 | 7.08989756549679e-09 | 11 | 126 | Glutamatergic synapse (KEGG):04724 |
| 0.000344422853611151 | 0.00872078665343435 | 4 | 70 | Long-term depression (KEGG):04730 |
| 0.000120892737745575 | 0.00347841377240676 | 5 | 101 | GnRH signaling pathway (KEGG):04912 |
| 0.000120892737745575 | 0.00347841377240676 | 5 | 101 | Melanogenesis (KEGG):04916 |
| 8.59341657850178e-05 | 0.00286296457589033 | 4 | 49 | Endocrine and other factor-regulated calcium reabsorption (KEGG):04961 |
| 4.21373863607217e-06 | 0.000242481505148516 | 6 | 89 | Salivary secretion (KEGG):04970 |
| 6.25241489427255e-08 | 9.89444657018632e-06 | 7 | 74 | Gastric acid secretion (KEGG):04971 |
| 0.000120892737745575 | 0.00347841377240676 | 5 | 101 | Pancreatic secretion (KEGG):04972 |
| 0.000363656682011917 | 0.00885364152744397 | 4 | 71 | Bile secretion (KEGG):04976 |
| 0.000147678504781227 | 0.00406436928376161 | 6 | 167 | Alzheimer's disease (KEGG):05010 |
| 5.25132748566414e-06 | 0.000277007524868783 | 5 | 53 | Amyotrophic lateral sclerosis (ALS) (KEGG):05014 |
| 0.00137006939143809 | 0.0271016851493847 | 4 | 101 | Integrin-mediated cell adhesion (Wikipathways):WP185 |
| 0.00105998327878395 | 0.0216441746925884 | 5 | 162 | Insulin Signaling (Wikipathways):WP481 |
| 0.000899153479686965 | 0.0196263500910982 | 3 | 40 | G13 Signaling Pathway (Wikipathways):WP524 |
| 7.26120519341067e-06 | 0.000353564837494535 | 7 | 149 | Calcium Regulation in the Cardiac Cell (Wikipathways):WP536 |
| 3.99045369969038e-07 | 5.05191438380803e-05 | 5 | 32 | Hypothetical Network for Drug Addiction (Wikipathways):WP666 |
| 1.04898152071803e-05 | 0.000442670201743008 | 8 | 220 | Signalling by NGF (Reactome):REACT_11061 |
| 0.000572840679598682 | 0.0129502910780702 | 4 | 80 | Opioid Signalling (Reactome):REACT_15295 |
| 3.458211091813e-06 | 0.000233586416362785 | 11 | 401 | Transmembrane transport of small molecules (Reactome):REACT_15518 |
| 1.42907936727847e-25 | 9.0460723948727e-23 | 23 | 197 | Synaptic Transmission (Reactome):REACT_13685 |
| 0.000327001188547684 | 0.00862465634794517 | 5 | 125 | Integration of energy metabolism (Reactome):REACT_1505 |
| 5.81501831171342e-08 | 9.89444657018632e-06 | 11 | 265 | Axon guidance (Reactome):REACT_18266 |
| 0.00177226596290773 | 0.033995283470321 | 5 | 182 | B Cell Receptor down reg. targets (Netpath):NetPath_12 |
| 8.96833935517651e-06 | 0.000405497057987624 | 4 | 28 | {DLG4,28} (Static Module):NA |
| 3.27539066315457e-06 | 0.000233586416362785 | 4 | 22 | {DNM1,22} (Static Module):NA |
| 0.000421984845315268 | 0.00989320026239129 | 3 | 31 | {NGF,31} (Static Module):NA |
| 0.000974496572601648 | 0.0205618776818948 | 2 | 10 | {PAK2,10} (Static Module):NA |
| 0.00194636065934882 | 0.0362366558049353 | 2 | 14 | {PRKCA,14} (Static Module):NA |
| 4.9483226177012e-07 | 5.22048036167477e-05 | 6 | 62 | {VAMP2,63} (Static Module):NA |
Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0051179 | localization | 9.74268200786426e-15 |
| GO:0019226 | transmission of nerve impulse | 9.74268200786426e-15 |
| GO:0044459 | plasma membrane part | 9.74268200786426e-15 |
| GO:0007268 | synaptic transmission | 1.35643883665414e-14 |
| GO:0003008 | system process | 3.26181352183431e-13 |
| GO:0030054 | cell junction | 5.72460589056865e-13 |
| GO:0016043 | cellular component organization and biogenesis | 6.03243416847754e-13 |
| GO:0016020 | membrane | 8.3421418952322e-13 |
| GO:0005886 | plasma membrane | 3.00629010962831e-12 |
| GO:0032501 | multicellular organismal process | 3.00629010962831e-12 |
| GO:0044425 | membrane part | 6.42247311607833e-12 |
| GO:0006810 | transport | 6.42247311607833e-12 |
| GO:0051234 | establishment of localization | 2.30216024961227e-11 |
| GO:0043005 | neuron projection | 4.20267118743778e-11 |
| GO:0007267 | cell-cell signaling | 2.7305457891388e-10 |
| GO:0016021 | integral to membrane | 1.00762367460598e-09 |
| GO:0031224 | intrinsic to membrane | 1.23795870012703e-09 |
| GO:0044456 | synapse part | 1.56727474738681e-09 |
| GO:0007399 | nervous system development | 1.22294962269787e-08 |
| GO:0045211 | postsynaptic membrane | 1.37869568553755e-08 |
| GO:0050877 | neurological system process | 1.8063884609109e-08 |
| GO:0048731 | system development | 7.14886614246929e-08 |
| GO:0044464 | cell part | 7.93491343954634e-08 |
| GO:0022857 | transmembrane transporter activity | 1.2080733259244e-07 |
| GO:0008021 | synaptic vesicle | 4.95713611810747e-07 |
| GO:0007215 | glutamate signaling pathway | 4.95713611810747e-07 |
| GO:0030136 | clathrin-coated vesicle | 4.95713611810747e-07 |
| GO:0001505 | regulation of neurotransmitter levels | 6.55765823094085e-07 |
| GO:0048856 | anatomical structure development | 6.55765823094085e-07 |
| GO:0006811 | ion transport | 7.99798788177793e-07 |
| GO:0022892 | substrate-specific transporter activity | 1.04534239984986e-06 |
| GO:0022891 | substrate-specific transmembrane transporter activity | 1.38621242685523e-06 |
| GO:0006996 | organelle organization and biogenesis | 1.44613301892787e-06 |
| GO:0045055 | regulated secretory pathway | 1.44613301892787e-06 |
| GO:0022836 | gated channel activity | 1.8257247924855e-06 |
| GO:0007154 | cell communication | 1.8257247924855e-06 |
| GO:0030135 | coated vesicle | 2.46412432685635e-06 |
| GO:0030182 | neuron differentiation | 2.87275086485279e-06 |
| GO:0005887 | integral to plasma membrane | 3.88994001782064e-06 |
| GO:0031226 | intrinsic to plasma membrane | 5.16872283174223e-06 |
| GO:0005515 | protein binding | 6.86625415477158e-06 |
| GO:0042995 | cell projection | 7.70056815869869e-06 |
| GO:0022838 | substrate specific channel activity | 8.08398871271606e-06 |
| GO:0048699 | generation of neurons | 8.08398871271606e-06 |
| GO:0048667 | neuron morphogenesis during differentiation | 8.08398871271606e-06 |
| GO:0048812 | neurite morphogenesis | 8.08398871271606e-06 |
| GO:0007269 | neurotransmitter secretion | 8.41439342398585e-06 |
| GO:0022803 | passive transmembrane transporter activity | 8.41439342398585e-06 |
| GO:0015267 | channel activity | 8.41439342398585e-06 |
| GO:0000904 | cellular morphogenesis during differentiation | 1.03604618625749e-05 |
| GO:0015075 | ion transmembrane transporter activity | 1.05945248279389e-05 |
| GO:0022008 | neurogenesis | 1.35130620432301e-05 |
| GO:0031175 | neurite development | 1.55827206207623e-05 |
| GO:0005509 | calcium ion binding | 2.73330428740047e-05 |
| GO:0031402 | sodium ion binding | 3.16284221933078e-05 |
| GO:0005216 | ion channel activity | 3.36335203348446e-05 |
| GO:0048666 | neuron development | 3.45858025516215e-05 |
| GO:0005874 | microtubule | 3.45858025516215e-05 |
| GO:0007010 | cytoskeleton organization and biogenesis | 3.45858025516215e-05 |
| GO:0031420 | alkali metal ion binding | 3.4719877052404e-05 |
| GO:0007017 | microtubule-based process | 5.23860981997384e-05 |
| GO:0045045 | secretory pathway | 5.98273637753155e-05 |
| GO:0006887 | exocytosis | 6.44040218187214e-05 |
| GO:0007409 | axonogenesis | 7.39880481415924e-05 |
| GO:0005875 | microtubule associated complex | 8.61349199385598e-05 |
| GO:0007275 | multicellular organismal development | 8.87170716888057e-05 |
| GO:0003001 | generation of a signal involved in cell-cell signaling | 0.000101501621706917 |
| GO:0030424 | axon | 0.000116998215531943 |
| GO:0008038 | neuron recognition | 0.000119030005702071 |
| GO:0005230 | extracellular ligand-gated ion channel activity | 0.000150463935756171 |
| GO:0030516 | regulation of axon extension | 0.00015381094211172 |
| GO:0004970 | ionotropic glutamate receptor activity | 0.000155992424496964 |
| GO:0050767 | regulation of neurogenesis | 0.000164370336440779 |
| GO:0030425 | dendrite | 0.000164370336440779 |
| GO:0048858 | cell projection morphogenesis | 0.000164370336440779 |
| GO:0032990 | cell part morphogenesis | 0.000164370336440779 |
| GO:0030030 | cell projection organization and biogenesis | 0.000164370336440779 |
| GO:0035235 | ionotropic glutamate receptor signaling pathway | 0.000172011087722756 |
| GO:0005234 | extracellular-glutamate-gated ion channel activity | 0.000172011087722756 |
| GO:0000902 | cell morphogenesis | 0.000172011087722756 |
| GO:0032989 | cellular structure morphogenesis | 0.000172011087722756 |
| GO:0046903 | secretion | 0.000190377310202258 |
| GO:0022610 | biological adhesion | 0.000192376142225121 |
| GO:0007155 | cell adhesion | 0.000192376142225121 |
| GO:0030955 | potassium ion binding | 0.000196120107707843 |
| GO:0051649 | establishment of cellular localization | 0.000197979433752903 |
| GO:0032940 | secretion by cell | 0.000200681446307282 |
| GO:0017157 | regulation of exocytosis | 0.000254540382055077 |
| GO:0051641 | cellular localization | 0.000256035947609557 |
| GO:0008324 | cation transmembrane transporter activity | 0.000288078769438492 |
| GO:0048167 | regulation of synaptic plasticity | 0.0003021180556749 |
| GO:0008066 | glutamate receptor activity | 0.000311903910683141 |
| GO:0048675 | axon extension | 0.000357979605576441 |
| GO:0031410 | cytoplasmic vesicle | 0.000367086920520027 |
| GO:0022834 | ligand-gated channel activity | 0.000390867641160272 |
| GO:0015276 | ligand-gated ion channel activity | 0.000390867641160272 |
| GO:0031982 | vesicle | 0.000402429450295212 |
| GO:0050803 | regulation of synapse structure and activity | 0.000402429450295212 |
| GO:0048489 | synaptic vesicle transport | 0.000402429450295212 |
| GO:0004971 | alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity | 0.000402521463769346 |
| GO:0016595 | glutamate binding | 0.000402521463769346 |
| GO:0030672 | synaptic vesicle membrane | 0.000402521463769346 |
| GO:0006814 | sodium ion transport | 0.000490704881059244 |
| GO:0016023 | cytoplasmic membrane-bound vesicle | 0.000501048308968536 |
| GO:0022843 | voltage-gated cation channel activity | 0.000501048308968536 |
| GO:0006813 | potassium ion transport | 0.000508694557505973 |
| GO:0030001 | metal ion transport | 0.000522091955119126 |
| GO:0031988 | membrane-bound vesicle | 0.00053784872292683 |
| GO:0031114 | regulation of microtubule depolymerization | 0.000676043539299965 |
| GO:0007026 | negative regulation of microtubule depolymerization | 0.000676043539299965 |
| GO:0007019 | microtubule depolymerization | 0.000761466181520716 |
| GO:0031111 | negative regulation of microtubule polymerization or depolymerization | 0.000761466181520716 |
| GO:0006812 | cation transport | 0.000795017476695107 |
| GO:0016192 | vesicle-mediated transport | 0.000892902343734273 |
| GO:0006928 | cell motility | 0.000898728929088817 |
| GO:0051674 | localization of cell | 0.000898728929088817 |
| GO:0046873 | metal ion transmembrane transporter activity | 0.0010036567046509 |
| GO:0007214 | gamma-aminobutyric acid signaling pathway | 0.00103167618473336 |
| GO:0045664 | regulation of neuron differentiation | 0.00103167618473336 |
| GO:0050770 | regulation of axonogenesis | 0.00103167618473336 |
| GO:0032502 | developmental process | 0.00103167618473336 |
| GO:0008328 | ionotropic glutamate receptor complex | 0.00108080629192991 |
| GO:0017146 | N-methyl-D-aspartate selective glutamate receptor complex | 0.00108080629192991 |
| GO:0060052 | neurofilament cytoskeleton organization and biogenesis | 0.00108080629192991 |
| GO:0008089 | anterograde axon cargo transport | 0.00108080629192991 |
| GO:0007413 | axonal fasciculation | 0.00108080629192991 |
| GO:0015630 | microtubule cytoskeleton | 0.00120508379288831 |
| GO:0005231 | excitatory extracellular ligand-gated ion channel activity | 0.00123446635637685 |
| GO:0031110 | regulation of microtubule polymerization or depolymerization | 0.00134169484154836 |
| GO:0015672 | monovalent inorganic cation transport | 0.00137656793000439 |
| GO:0005261 | cation channel activity | 0.00149233489660535 |
| GO:0004972 | N-methyl-D-aspartate selective glutamate receptor activity | 0.00153208802207916 |
| GO:0005678 | chromatin assembly complex | 0.00153208802207916 |
| GO:0005737 | cytoplasm | 0.00157435855401658 |
| GO:0022832 | voltage-gated channel activity | 0.00166858551309482 |
| GO:0005244 | voltage-gated ion channel activity | 0.00166858551309482 |
| GO:0031109 | microtubule polymerization or depolymerization | 0.00170079162506074 |
| GO:0016477 | cell migration | 0.00186145114915535 |
| GO:0005624 | membrane fraction | 0.0019158573457195 |
| GO:0006904 | vesicle docking during exocytosis | 0.00199000128416068 |
| GO:0060053 | neurofilament cytoskeleton | 0.00199000128416068 |
| GO:0005883 | neurofilament | 0.00199000128416068 |
| GO:0007158 | neuron adhesion | 0.00199000128416068 |
| GO:0005200 | structural constituent of cytoskeleton | 0.00207964971777843 |
| GO:0001764 | neuron migration | 0.00227226111901528 |
| GO:0019717 | synaptosome | 0.00227226111901528 |
| GO:0001504 | neurotransmitter uptake | 0.00249006597303352 |
| GO:0005313 | L-glutamate transmembrane transporter activity | 0.00249006597303352 |
| GO:0008088 | axon cargo transport | 0.00249006597303352 |
| GO:0003730 | mRNA 3'-UTR binding | 0.00249006597303352 |
| GO:0016079 | synaptic vesicle exocytosis | 0.00249006597303352 |
| GO:0015277 | kainate selective glutamate receptor activity | 0.00249006597303352 |
| GO:0022406 | membrane docking | 0.00251495597097151 |
| GO:0048278 | vesicle docking | 0.00251495597097151 |
| GO:0008037 | cell recognition | 0.00251495597097151 |
| GO:0015296 | anion:cation symporter activity | 0.00269964219094422 |
| GO:0015172 | acidic amino acid transmembrane transporter activity | 0.00309190314005995 |
| GO:0007018 | microtubule-based movement | 0.00375212709806153 |
| GO:0007611 | learning and/or memory | 0.00375212709806153 |
| GO:0048869 | cellular developmental process | 0.00375212709806153 |
| GO:0030154 | cell differentiation | 0.00375212709806153 |
| GO:0051261 | protein depolymerization | 0.00423585193079648 |
| GO:0044430 | cytoskeletal part | 0.00436058735428454 |
| GO:0016917 | GABA receptor activity | 0.00445723292898774 |
| GO:0007613 | memory | 0.00447255771990586 |
| GO:0030705 | cytoskeleton-dependent intracellular transport | 0.00522711427907329 |
| GO:0030295 | protein kinase activator activity | 0.00522711427907329 |
| GO:0050768 | negative regulation of neurogenesis | 0.00522711427907329 |
| GO:0042734 | presynaptic membrane | 0.00522711427907329 |
| GO:0051129 | negative regulation of cellular component organization and biogenesis | 0.0057468843562058 |
| GO:0015813 | L-glutamate transport | 0.00601978708337079 |
| GO:0015800 | acidic amino acid transport | 0.00601978708337079 |
| GO:0008509 | anion transmembrane transporter activity | 0.00674370394721996 |
| GO:0045104 | intermediate filament cytoskeleton organization and biogenesis | 0.00692570762928132 |
| GO:0007411 | axon guidance | 0.00692716814399229 |
| GO:0005272 | sodium channel activity | 0.00725080875065966 |
| GO:0045103 | intermediate filament-based process | 0.00779337491174136 |
| GO:0017153 | sodium:dicarboxylate symporter activity | 0.00779337491174136 |
| GO:0005856 | cytoskeleton | 0.00819544965416257 |
| GO:0008289 | lipid binding | 0.00873832035364788 |
| GO:0016050 | vesicle organization and biogenesis | 0.00873832035364788 |
| GO:0005310 | dicarboxylic acid transmembrane transporter activity | 0.00971883926758501 |
| GO:0005391 | sodium:potassium-exchanging ATPase activity | 0.00971883926758501 |
| GO:0006835 | dicarboxylic acid transport | 0.00971883926758501 |
| GO:0007417 | central nervous system development | 0.0105500180514039 |
| GO:0005516 | calmodulin binding | 0.0105562419282572 |
| GO:0003777 | microtubule motor activity | 0.0105562419282572 |
| GO:0050793 | regulation of developmental process | 0.0105641537074279 |
| GO:0019209 | kinase activator activity | 0.0105641537074279 |
| GO:0030426 | growth cone | 0.0105641537074279 |
| GO:0000267 | cell fraction | 0.0114152792701489 |
| GO:0030427 | site of polarized growth | 0.011595801421391 |
| GO:0019905 | syntaxin binding | 0.011595801421391 |
| GO:0044424 | intracellular part | 0.0118030755624839 |
| GO:0016597 | amino acid binding | 0.0127213725888923 |
| GO:0048468 | cell development | 0.0129367444784535 |
| GO:0007165 | signal transduction | 0.0134499930935259 |
| GO:0000149 | SNARE binding | 0.0138144318598356 |
| GO:0005248 | voltage-gated sodium channel activity | 0.0150827132759286 |
| GO:0006836 | neurotransmitter transport | 0.0156746777931564 |
| GO:0065007 | biological regulation | 0.0167572865540087 |
| GO:0005249 | voltage-gated potassium channel activity | 0.0167572865540087 |
| GO:0046056 | dADP metabolic process | 0.0167572865540087 |
| GO:0048499 | synaptic vesicle membrane organization and biogenesis | 0.0167572865540087 |
| GO:0030285 | integral to synaptic vesicle membrane | 0.0167572865540087 |
| GO:0009153 | purine deoxyribonucleotide biosynthetic process | 0.0167572865540087 |
| GO:0033596 | TSC1-TSC2 complex | 0.0167572865540087 |
| GO:0006172 | ADP biosynthetic process | 0.0167572865540087 |
| GO:0009183 | purine deoxyribonucleoside diphosphate biosynthetic process | 0.0167572865540087 |
| GO:0006173 | dADP biosynthetic process | 0.0167572865540087 |
| GO:0009151 | purine deoxyribonucleotide metabolic process | 0.0167572865540087 |
| GO:0009182 | purine deoxyribonucleoside diphosphate metabolic process | 0.0167572865540087 |
| GO:0046031 | ADP metabolic process | 0.0167572865540087 |
| GO:0006713 | glucocorticoid catabolic process | 0.0167572865540087 |
| GO:0008090 | retrograde axon cargo transport | 0.0167572865540087 |
| GO:0033693 | neurofilament bundle assembly | 0.0167572865540087 |
| GO:0001778 | plasma membrane repair | 0.0167572865540087 |
| GO:0015319 | sodium:inorganic phosphate symporter activity | 0.0167572865540087 |
| GO:0003924 | GTPase activity | 0.0172233241039893 |
| GO:0005871 | kinesin complex | 0.0220083606191097 |
| GO:0007610 | behavior | 0.0229364197715432 |
| GO:0006334 | nucleosome assembly | 0.0243790753631391 |
| GO:0009653 | anatomical structure morphogenesis | 0.0277509525808598 |
| GO:0051128 | regulation of cellular component organization and biogenesis | 0.0279637116678751 |
| GO:0015179 | L-amino acid transmembrane transporter activity | 0.0279637116678751 |
| GO:0000226 | microtubule cytoskeleton organization and biogenesis | 0.0293427946734613 |
| GO:0007173 | epidermal growth factor receptor signaling pathway | 0.0294215737162022 |
| GO:0000287 | magnesium ion binding | 0.0294215737162022 |
| GO:0007242 | intracellular signaling cascade | 0.0294215737162022 |
| GO:0051248 | negative regulation of protein metabolic process | 0.0294215737162022 |
| GO:0003729 | mRNA binding | 0.0294215737162022 |
| GO:0016533 | cyclin-dependent protein kinase 5 activator complex | 0.0294215737162022 |
| GO:0045298 | tubulin complex | 0.0294215737162022 |
| GO:0009188 | ribonucleoside diphosphate biosynthetic process | 0.0294215737162022 |
| GO:0050774 | negative regulation of dendrite morphogenesis | 0.0294215737162022 |
| GO:0045110 | intermediate filament bundle assembly | 0.0294215737162022 |
| GO:0016188 | synaptic vesicle maturation | 0.0294215737162022 |
| GO:0019896 | axon transport of mitochondrion | 0.0294215737162022 |
| GO:0016534 | cyclin-dependent protein kinase 5 activator activity | 0.0294215737162022 |
| GO:0009180 | purine ribonucleoside diphosphate biosynthetic process | 0.0294215737162022 |
| GO:0016080 | synaptic vesicle targeting | 0.0294215737162022 |
| GO:0009179 | purine ribonucleoside diphosphate metabolic process | 0.0294215737162022 |
| GO:0043539 | protein serine/threonine kinase activator activity | 0.0294215737162022 |
| GO:0045162 | clustering of voltage-gated sodium channels | 0.0294215737162022 |
| GO:0009136 | purine nucleoside diphosphate biosynthetic process | 0.0294215737162022 |
| GO:0045844 | positive regulation of striated muscle development | 0.0294215737162022 |
| GO:0017075 | syntaxin-1 binding | 0.0294215737162022 |
| GO:0009135 | purine nucleoside diphosphate metabolic process | 0.0294215737162022 |
| GO:0044433 | cytoplasmic vesicle part | 0.0303840209562932 |
| GO:0031497 | chromatin assembly | 0.0318408539137827 |
| GO:0051049 | regulation of transport | 0.0325095942265898 |
| GO:0005267 | potassium channel activity | 0.0337085334015997 |
| GO:0005543 | phospholipid binding | 0.0338443268177897 |
| GO:0012506 | vesicle membrane | 0.0343441970059596 |
| GO:0019201 | nucleotide kinase activity | 0.0343441970059596 |
| GO:0005343 | organic acid:sodium symporter activity | 0.0343441970059596 |
| GO:0015294 | solute:cation symporter activity | 0.034997538194679 |
| GO:0050808 | synapse organization and biogenesis | 0.035695384431096 |
| GO:0004890 | GABA-A receptor activity | 0.035695384431096 |
| GO:0016337 | cell-cell adhesion | 0.0384093966827012 |
| GO:0016585 | chromatin remodeling complex | 0.0390079199515745 |
| GO:0035253 | ciliary rootlet | 0.0400307634611287 |
| GO:0035259 | glucocorticoid receptor binding | 0.0400307634611287 |
| GO:0030517 | negative regulation of axon extension | 0.0400307634611287 |
| GO:0008140 | cAMP response element binding protein binding | 0.0400307634611287 |
| GO:0048814 | regulation of dendrite morphogenesis | 0.0400307634611287 |
| GO:0000309 | nicotinamide-nucleotide adenylyltransferase activity | 0.0400307634611287 |
| GO:0045666 | positive regulation of neuron differentiation | 0.0400307634611287 |
| GO:0030297 | transmembrane receptor protein tyrosine kinase activator activity | 0.0400307634611287 |
| GO:0004705 | JUN kinase activity | 0.0400307634611287 |
| GO:0019987 | negative regulation of anti-apoptosis | 0.0400307634611287 |
| GO:0016081 | synaptic vesicle docking during exocytosis | 0.0400307634611287 |
| GO:0005905 | coated pit | 0.0407257963730632 |
| GO:0046777 | protein amino acid autophosphorylation | 0.0422535810058863 |
| GO:0043176 | amine binding | 0.0422535810058863 |
| GO:0022607 | cellular component assembly | 0.0422835106967054 |
| GO:0048503 | GPI anchor binding | 0.042406697896614 |
| GO:0016540 | protein autoprocessing | 0.0455104025210343 |
| GO:0015293 | symporter activity | 0.0467123560448409 |
| GO:0022804 | active transmembrane transporter activity | 0.0469144032018907 |
| GO:0044463 | cell projection part | 0.0469144032018907 |
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0 |
| MA0004.1 | 0.000105595 |
| MA0006.1 | 4.38182e-09 |
| MA0007.1 | 0.148393 |
| MA0009.1 | 0.308703 |
| MA0014.1 | 0 |
| MA0017.1 | 2.34031 |
| MA0019.1 | 0.197017 |
| MA0024.1 | 7.02615e-05 |
| MA0025.1 | 0.217446 |
| MA0027.1 | 0.546944 |
| MA0028.1 | 3.37515e-16 |
| MA0029.1 | 0.100049 |
| MA0030.1 | 0.501249 |
| MA0031.1 | 0.936406 |
| MA0038.1 | 0.193599 |
| MA0040.1 | 0.877608 |
| MA0041.1 | 3.12439 |
| MA0042.1 | 1.91081 |
| MA0043.1 | 0.00163088 |
| MA0046.1 | 1.27931 |
| MA0048.1 | 1.06076e-15 |
| MA0050.1 | 0.0735227 |
| MA0051.1 | 0.0450936 |
| MA0052.1 | 0.116485 |
| MA0055.1 | 2.96049e-14 |
| MA0056.1 | 0 |
| MA0057.1 | 5.6254e-09 |
| MA0058.1 | 4.69137e-06 |
| MA0059.1 | 0.0556006 |
| MA0060.1 | 0 |
| MA0061.1 | 1.07009e-06 |
| MA0063.1 | 0 |
| MA0066.1 | 0.0258409 |
| MA0067.1 | 0.0941412 |
| MA0068.1 | 9.03496e-06 |
| MA0069.1 | 0.722423 |
| MA0070.1 | 2.02336 |
| MA0071.1 | 2.16306 |
| MA0072.1 | 0.390669 |
| MA0073.1 | 0 |
| MA0074.1 | 0.807099 |
| MA0076.1 | 2.79655e-14 |
| MA0077.1 | 1.22815 |
| MA0078.1 | 0.99349 |
| MA0081.1 | 0.0701585 |
| MA0083.1 | 0.000159707 |
| MA0084.1 | 1.12651 |
| MA0087.1 | 1.08728 |
| MA0088.1 | 9.81627e-10 |
| MA0089.1 | 0 |
| MA0090.1 | 0.0480076 |
| MA0091.1 | 3.78851 |
| MA0092.1 | 0.0891657 |
| MA0093.1 | 1.56007e-07 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 3.89183e-05 |
| MA0101.1 | 2.06436e-05 |
| MA0103.1 | 1.04774 |
| MA0105.1 | 4.20289e-05 |
| MA0106.1 | 0.0125641 |
| MA0107.1 | 5.21078e-06 |
| MA0108.2 | 0.00152612 |
| MA0109.1 | 0 |
| MA0111.1 | 0.0212785 |
| MA0113.1 | 1.36615 |
| MA0114.1 | 0.53081 |
| MA0115.1 | 4.37855 |
| MA0116.1 | 2.28079e-05 |
| MA0117.1 | 0.0205668 |
| MA0119.1 | 0.00189379 |
| MA0122.1 | 0.0985644 |
| MA0124.1 | 1.39055 |
| MA0125.1 | 1.49412 |
| MA0130.1 | 0 |
| MA0131.1 | 2.08034e-05 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 6.09118 |
| MA0136.1 | 0.00349182 |
| MA0139.1 | 1.45763e-05 |
| MA0140.1 | 0.00534574 |
| MA0141.1 | 1.48613 |
| MA0142.1 | 0.925159 |
| MA0143.1 | 0.30903 |
| MA0144.1 | 0.148421 |
| MA0145.1 | 1.9192e-12 |
| MA0146.1 | 0 |
| MA0147.1 | 8.83321e-09 |
| MA0148.1 | 1.36525 |
| MA0149.1 | 0.0012197 |
| MA0062.2 | 0 |
| MA0035.2 | 0.0673205 |
| MA0039.2 | 0 |
| MA0138.2 | 0.00348339 |
| MA0002.2 | 0.168056 |
| MA0137.2 | 0.0351918 |
| MA0104.2 | 8.19678e-16 |
| MA0047.2 | 1.8581 |
| MA0112.2 | 2.07155e-10 |
| MA0065.2 | 0.177532 |
| MA0150.1 | 0.00257586 |
| MA0151.1 | 0 |
| MA0152.1 | 2.61197 |
| MA0153.1 | 1.5973 |
| MA0154.1 | 0.0786723 |
| MA0155.1 | 4.21456e-05 |
| MA0156.1 | 1.22103e-07 |
| MA0157.1 | 1.22397 |
| MA0158.1 | 0 |
| MA0159.1 | 0.603511 |
| MA0160.1 | 0.556634 |
| MA0161.1 | 0 |
| MA0162.1 | 0 |
| MA0163.1 | 9.63363e-14 |
| MA0164.1 | 0.45452 |
| MA0080.2 | 0.000475665 |
| MA0018.2 | 0.000387008 |
| MA0099.2 | 4.6592e-06 |
| MA0079.2 | 0 |
| MA0102.2 | 0.961797 |
| MA0258.1 | 0.0058941 |
| MA0259.1 | 1.82319e-09 |
| MA0442.1 | 0 |
ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data
No analysis results for this cluster
Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data
