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Coexpression cluster:C1106: Difference between revisions

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|tfbs_overrepresentation_for_novel_motifs=0.392069,0.100351,0.384703,0.529489,0.343148,0.52784,0.604235,0.226729,0.224331,0.200685,0.497563,0.647852,0.184039,0.592674,0.341795,0.365029,0.827563,0.28906,0.19568,0.32524,1.77222,0.0646572,0.520063,0.338096,0.430372,0.670692,0.164928,0.517892,0.346214,0.150685,0.475674,0.864517,0.257226,0.546594,0.309012,0.442372,0.825031,0.529001,0.282922,0.207499,0.829015,0.459366,0.0729319,0.340293,0.0257952,0.415364,0.60533,0.486696,0.511111,0.346342,0.684981,0.617179,0.752493,0.941629,1.09491,0.595623,0.350547,0.562713,0.459282,0.561701,0.905643,0.60771,0.224801,0.799729,0.625758,0.76514,1.18348,1.55228,0.854088,1.38987,0.4462,0.232216,0.115253,1.0929,0.531388,0.168304,0.156354,0.782748,0.850825,0.424224,0.580264,0.798651,0.625403,0.229431,1.04131,0.0324537,3.57827,0.146388,0.711163,1.65172,1.27705,1.01423,2.04389,0.73028,0.343884,0.277058,0.194299,0.924148,0.715799,0.413337,0.28424,0.875714,0.918549,0.831244,0.753567,0.493026,0.815341,0.589207,0.43012,0.327379,1.02467,0.915771,0.379203,0.507004,1.22894,0.304323,0.155979,0.474472,0.762789,0.736663,1.0846,1.68811,0.525076,0.636741,1.33983,0.783512,0.597853,0.886402,1.12733,0.27799,1.01492,0.47854,1.14174,0.633392,1.28996,0.854586,0.469685,0.518459,1.24743,2.10682,1.70417,1.21002,0.59959,0.920609,0.755332,0.554217,0.738579,1.94751,1.15519,0.26104,0.345641,0.0685123,1.0153,0.216774,0.607223,1.42052,0.694887,0.329354,0.430431,0.401655,1.2088,0.996724,0.850033,0.404861,0.7715,0.624608,0.24928,0.602897,0.00626991
}}
}}

Revision as of 14:41, 26 November 2012


Full id: C1106_pineal_occipital_middle_parietal_olfactory_amygdala_caudate



Phase1 CAGE Peaks

Hg19::chr10:115802982..115802997,+p@chr10:115802982..115802997
+
Hg19::chr4:21056328..21056331,-p@chr4:21056328..21056331
-
Hg19::chr4:21418996..21419012,-p@chr4:21418996..21419012
-
Hg19::chr4:21419073..21419100,-p@chr4:21419073..21419100
-
Hg19::chr4:21594781..21594810,-p@chr4:21594781..21594810
-
Hg19::chr4:21867081..21867096,-p1@AK057907
Hg19::chr8:105265029..105265058,+p@chr8:105265029..105265058
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube6.08e-11156
neural rod6.08e-11156
future spinal cord6.08e-11156
neural keel6.08e-11156
regional part of nervous system1.16e-10653
regional part of brain1.16e-10653
brain3.67e-9368
future brain3.67e-9368
regional part of forebrain4.86e-8941
forebrain4.86e-8941
anterior neural tube4.86e-8941
future forebrain4.86e-8941
central nervous system9.71e-8981
neural plate2.04e-8482
presumptive neural plate2.04e-8482
neurectoderm4.62e-8086
nervous system4.85e-7989
brain grey matter1.33e-7634
gray matter1.33e-7634
cerebral hemisphere1.22e-7532
telencephalon6.54e-7134
regional part of telencephalon4.71e-7032
pre-chordal neural plate3.03e-6561
ecto-epithelium1.44e-64104
regional part of cerebral cortex3.95e-6022
adult organism1.09e-55114
neocortex3.13e-5320
cerebral cortex1.39e-5225
pallium1.39e-5225
structure with developmental contribution from neural crest1.99e-51132
ectoderm-derived structure1.28e-40171
ectoderm1.28e-40171
presumptive ectoderm1.28e-40171
organ system subdivision2.46e-27223
tube3.34e-27192
basal ganglion1.16e-259
nuclear complex of neuraxis1.16e-259
aggregate regional part of brain1.16e-259
collection of basal ganglia1.16e-259
cerebral subcortex1.16e-259
neural nucleus3.49e-259
nucleus of brain3.49e-259
posterior neural tube3.70e-2215
chordal neural plate3.70e-2215
gyrus3.93e-226
anatomical conduit9.24e-20240
diencephalon4.42e-197
future diencephalon4.42e-197
limbic system9.60e-195
telencephalic nucleus1.03e-187
segmental subdivision of hindbrain3.30e-1812
hindbrain3.30e-1812
presumptive hindbrain3.30e-1812
parietal lobe3.44e-185
segmental subdivision of nervous system1.05e-1613
organ part2.69e-16218
regional part of diencephalon3.23e-164
corpus striatum2.44e-154
striatum2.44e-154
ventral part of telencephalon2.44e-154
future corpus striatum2.44e-154
epithelium3.11e-15306
cell layer5.51e-15309
brainstem1.30e-146
regional part of metencephalon2.35e-149
metencephalon2.35e-149
future metencephalon2.35e-149
anatomical cluster6.93e-14373
temporal lobe2.22e-136
caudate-putamen2.37e-123
dorsal striatum2.37e-123
frontal cortex3.33e-123
occipital lobe3.59e-125
multi-tissue structure1.04e-11342
pons1.88e-113
gland of diencephalon2.58e-094
neuroendocrine gland2.58e-094
pineal body3.24e-092
regional part of epithalamus3.24e-092
secretory circumventricular organ3.24e-092
circumventricular organ3.24e-092
epithalamus3.24e-092
middle frontal gyrus6.26e-092
amygdala7.87e-092
middle temporal gyrus9.16e-092
caudate nucleus9.16e-092
future caudate nucleus9.16e-092
dorsal plus ventral thalamus1.03e-082
thalamic complex1.03e-082
Ammon's horn1.24e-082
lobe parts of cerebral cortex1.24e-082
hippocampal formation1.24e-082
limbic lobe1.24e-082
globus pallidus2.51e-082
pallidum2.51e-082
locus ceruleus2.81e-082
brainstem nucleus2.81e-082
hindbrain nucleus2.81e-082
organ4.57e-08503


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.