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Coexpression cluster:C105

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Full id: C105_heart_skeletal_occipital_hippocampus_acute_Sebocyte_penis



Phase1 CAGE Peaks

  Short description
Hg19::chr12:323699..323719,- p1@SLC6A12
Hg19::chr17:22020689..22020720,+ p@chr17:22020689..22020720
+
Hg19::chr17:22020726..22020758,- -
p@chr17:22020726..22020758
Hg19::chr17:22020770..22020781,- p@chr17:22020770..22020781
-
Hg19::chr17:22031915..22031917,- p@chr17:22031915..22031917
-
Hg19::chr4:129002899..129002914,- p@chr4:129002899..129002914
-
Hg19::chr4:65473912..65473913,- p@chr4:65473912..65473913
-
Hg19::chr5:134259906..134259937,- p1@ENST00000501056
Hg19::chr5:134263666..134263678,- p3@MTND4P12
Hg19::chr5:99387824..99387861,- p@chr5:99387824..99387861
-
Hg19::chr5:99388558..99388603,+ p@chr5:99388558..99388603
+
Hg19::chr8:100508096..100508130,+ +
p@chr8:100508096..100508130
Hg19::chr8:13357482..13357490,- p23@DLC1
Hg19::chrM:100..125,- p@chrM:100..125
-
Hg19::chrM:10041..10104,- p@chrM:10041..10104
-
Hg19::chrM:10113..10131,- p@chrM:10113..10131
-
Hg19::chrM:10138..10169,- p@chrM:10138..10169
-
Hg19::chrM:10175..10198,- p@chrM:10175..10198
-
Hg19::chrM:10219..10233,- p@chrM:10219..10233
-
Hg19::chrM:10235..10366,- p@chrM:10235..10366
-
Hg19::chrM:10371..10407,- p@chrM:10371..10407
-
Hg19::chrM:10600..10633,- p@chrM:10600..10633
-
Hg19::chrM:10660..10715,- p@chrM:10660..10715
-
Hg19::chrM:10807..10818,- p@chrM:10807..10818
-
Hg19::chrM:10826..10837,+ p10@uc004cov.3
Hg19::chrM:10862..10891,- p@chrM:10862..10891
-
Hg19::chrM:10910..10956,- p@chrM:10910..10956
-
Hg19::chrM:11173..11190,- p@chrM:11173..11190
-
Hg19::chrM:11198..11226,- p@chrM:11198..11226
-
Hg19::chrM:11250..11434,- p@chrM:11250..11434
-
Hg19::chrM:11460..11479,- p@chrM:11460..11479
-
Hg19::chrM:11484..11500,- p@chrM:11484..11500
-
Hg19::chrM:11586..11598,- p@chrM:11586..11598
-
Hg19::chrM:11771..11794,- p@chrM:11771..11794
-
Hg19::chrM:11798..11820,- p@chrM:11798..11820
-
Hg19::chrM:11825..11838,- p@chrM:11825..11838
-
Hg19::chrM:11850..11887,- p@chrM:11850..11887
-
Hg19::chrM:11889..11901,- p@chrM:11889..11901
-
Hg19::chrM:11909..11930,- p@chrM:11909..11930
-
Hg19::chrM:12009..12047,- p@chrM:12009..12047
-
Hg19::chrM:12049..12060,- p@chrM:12049..12060
-
Hg19::chrM:12118..12142,- p@chrM:12118..12142
-
Hg19::chrM:12200..12224,- p@chrM:12200..12224
-
Hg19::chrM:12227..12244,- p@chrM:12227..12244
-
Hg19::chrM:12293..12317,- p@chrM:12293..12317
-
Hg19::chrM:12349..12391,- p@chrM:12349..12391
-
Hg19::chrM:12407..12424,- p@chrM:12407..12424
-
Hg19::chrM:12425..12491,- p@chrM:12425..12491
-
Hg19::chrM:12538..12581,- p@chrM:12538..12581
-
Hg19::chrM:12582..12596,- p@chrM:12582..12596
-
Hg19::chrM:12608..12692,- p@chrM:12608..12692
-
Hg19::chrM:12698..12719,- p@chrM:12698..12719
-
Hg19::chrM:12727..12771,- p@chrM:12727..12771
-
Hg19::chrM:129..155,- p@chrM:129..155
-
Hg19::chrM:12900..12911,- p@chrM:12900..12911
-
Hg19::chrM:12918..12928,- p@chrM:12918..12928
-
Hg19::chrM:12936..12986,- p@chrM:12936..12986
-
Hg19::chrM:13014..13040,- p@chrM:13014..13040
-
Hg19::chrM:13106..13131,- p@chrM:13106..13131
-
Hg19::chrM:13152..13172,- p@chrM:13152..13172
-
Hg19::chrM:13173..13215,- -
p@chrM:13173..13215
Hg19::chrM:13265..13314,- p@chrM:13265..13314
-
Hg19::chrM:13367..13411,- p@chrM:13367..13411
-
Hg19::chrM:13472..13515,- p@chrM:13472..13515
-
Hg19::chrM:13592..13599,- p@chrM:13592..13599
-
Hg19::chrM:13640..13698,- p@chrM:13640..13698
-
Hg19::chrM:13707..13718,+ p@chrM:13707..13718
+
Hg19::chrM:13721..13732,- p@chrM:13721..13732
-
Hg19::chrM:13734..13739,- p@chrM:13734..13739
-
Hg19::chrM:13741..13762,- p@chrM:13741..13762
-
Hg19::chrM:13777..13788,- p@chrM:13777..13788
-
Hg19::chrM:13816..13827,- p@chrM:13816..13827
-
Hg19::chrM:13830..13849,- p@chrM:13830..13849
-
Hg19::chrM:13892..13906,- p@chrM:13892..13906
-
Hg19::chrM:14011..14030,- p@chrM:14011..14030
-
Hg19::chrM:14031..14055,- p@chrM:14031..14055
-
Hg19::chrM:14060..14073,- p@chrM:14060..14073
-
Hg19::chrM:14092..14104,- p@chrM:14092..14104
-
Hg19::chrM:14105..14119,- p@chrM:14105..14119
-
Hg19::chrM:14290..14295,- p@chrM:14290..14295
-
Hg19::chrM:14297..14310,- p@chrM:14297..14310
-
Hg19::chrM:14313..14352,- p@chrM:14313..14352
-
Hg19::chrM:14366..14421,- p@chrM:14366..14421
-
Hg19::chrM:14471..14537,- p@chrM:14471..14537
-
Hg19::chrM:14562..14596,- p@chrM:14562..14596
-
Hg19::chrM:14628..14668,+ p2@uc004coy.2
Hg19::chrM:14741..14767,+ p1@uc004coy.2
Hg19::chrM:14747..14817,- p@chrM:14747..14817
-
Hg19::chrM:14842..14851,- p@chrM:14842..14851
-
Hg19::chrM:14855..14894,- p@chrM:14855..14894
-
Hg19::chrM:14945..14983,- -
p@chrM:14945..14983
Hg19::chrM:15064..15075,- p@chrM:15064..15075
-
Hg19::chrM:15096..15105,- p@chrM:15096..15105
-
Hg19::chrM:15135..15147,- p@chrM:15135..15147
-
Hg19::chrM:15179..15191,- p@chrM:15179..15191
-
Hg19::chrM:15224..15235,- p22@BC006482
Hg19::chrM:15275..15296,- p13@BC006482
Hg19::chrM:15340..15352,- p17@BC006482
Hg19::chrM:15354..15374,- p9@BC006482
Hg19::chrM:15388..15399,+ p4@AF391805
Hg19::chrM:15414..15419,- p24@BC006482
Hg19::chrM:15438..15462,- p5@BC006482
Hg19::chrM:15464..15549,- p1@BC006482
Hg19::chrM:15563..15579,- p16@BC006482
Hg19::chrM:15581..15592,- p20@BC006482
Hg19::chrM:15596..15616,- p14@BC006482
Hg19::chrM:15618..15638,- p12@BC006482
Hg19::chrM:15645..15705,- p2@BC006482
Hg19::chrM:15706..15711,- p25@BC006482
Hg19::chrM:15712..15759,- p3@BC006482
Hg19::chrM:15773..15795,- p10@BC006482
Hg19::chrM:15802..15811,- p23@BC006482
Hg19::chrM:15819..15846,- p7@BC006482
Hg19::chrM:15847..15868,- p8@BC006482
Hg19::chrM:15915..15965,- p4@BC006482
Hg19::chrM:15949..15963,+ p5@uc004coz.1
Hg19::chrM:15983..15990,- p26@BC006482
Hg19::chrM:16003..16019,- p15@BC006482
Hg19::chrM:16023..16035,- p19@BC006482
Hg19::chrM:16090..16102,- p21@BC006482
Hg19::chrM:16152..16172,- p11@BC006482
Hg19::chrM:16173..16187,- p18@BC006482
Hg19::chrM:16197..16208,+ p8@uc004coz.1
Hg19::chrM:16213..16268,- p@chrM:16213..16268
-
Hg19::chrM:16446..16467,- p@chrM:16446..16467
-
Hg19::chrM:16492..16561,- p@chrM:16492..16561
-
Hg19::chrM:165..176,- p@chrM:165..176
-
Hg19::chrM:1668..1680,+ p1@uc004cos.3
Hg19::chrM:179..196,- p@chrM:179..196
-
Hg19::chrM:262..309,- p2@uc004coq.3
Hg19::chrM:2738..2749,- p@chrM:2738..2749
-
Hg19::chrM:3226..3246,+ p1@AK074482
Hg19::chrM:3251..3270,- p@chrM:3251..3270
-
Hg19::chrM:3374..3393,- p@chrM:3374..3393
-
Hg19::chrM:3402..3418,- p@chrM:3402..3418
-
Hg19::chrM:3449..3493,- p@chrM:3449..3493
-
Hg19::chrM:3504..3515,- p@chrM:3504..3515
-
Hg19::chrM:3516..3532,- p@chrM:3516..3532
-
Hg19::chrM:3533..3576,- p@chrM:3533..3576
-
Hg19::chrM:3612..3632,- p@chrM:3612..3632
-
Hg19::chrM:3633..3659,- p@chrM:3633..3659
-
Hg19::chrM:3668..3694,- p@chrM:3668..3694
-
Hg19::chrM:3750..3757,- p@chrM:3750..3757
-
Hg19::chrM:3758..3774,- p@chrM:3758..3774
-
Hg19::chrM:3780..3796,- p@chrM:3780..3796
-
Hg19::chrM:3805..3823,- p@chrM:3805..3823
-
Hg19::chrM:3880..3914,- p@chrM:3880..3914
-
Hg19::chrM:3919..3947,- p@chrM:3919..3947
-
Hg19::chrM:4287..4313,+ p1@S81656
Hg19::chrM:4431..4475,+ p2@AK026903
Hg19::chrM:48..67,- p@chrM:48..67
-
Hg19::chrM:4909..4987,- p2@AK000561
Hg19::chrM:4991..5023,- p7@AK000561
Hg19::chrM:5348..5405,- p3@AK000561
Hg19::chrM:5403..5414,+ p11@uc011mfh.1
Hg19::chrM:5421..5456,- p1@AK000561
Hg19::chrM:5471..5515,- p4@AK000561
Hg19::chrM:5526..5536,- p10@AK000561
Hg19::chrM:5824..5838,+ p9@uc011mfh.1
Hg19::chrM:6238..6295,- p@chrM:6238..6295
-
Hg19::chrM:6372..6425,- p@chrM:6372..6425
-
Hg19::chrM:6451..6466,- p@chrM:6451..6466
-
Hg19::chrM:6505..6521,- p@chrM:6505..6521
-
Hg19::chrM:6936..6954,- p1@U85268
Hg19::chrM:7165..7184,- p3@U85268
Hg19::chrM:7708..7733,- p3@BC033150
Hg19::chrM:7808..7841,- p2@BC033150
Hg19::chrM:7884..7945,- p1@BC033150
Hg19::chrM:8112..8200,+ p6@uc011mfi.1
Hg19::chrM:8145..8212,- p@chrM:8145..8212
-
Hg19::chrM:8456..8497,- p@chrM:8456..8497
-
Hg19::chrM:8483..8501,+ p7@uc011mfi.1
Hg19::chrM:8534..8546,+ p9@uc011mfi.1
Hg19::chrM:8667..8702,- p@chrM:8667..8702
-
Hg19::chrM:9134..9163,+ p8@uc011mfi.1
Hg19::chrM:9324..9378,- p2@AF271776
Hg19::chrM:9485..9494,+ p3@BC023992
Hg19::chrM:9495..9535,+ p1@BC023992
Hg19::chrM:9781..9808,- p@chrM:9781..9808
-
Hg19::chrM:9833..9922,- p@chrM:9833..9922
-
Hg19::chrM:9933..9974,- p@chrM:9933..9974
-
Hg19::chrM:9984..10028,- p@chrM:9984..10028
-


Enriched pathways on this co-expression cluster
Summary:


Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset


data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster
Summary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner



link to source dataset


data

GO IDGO nameFDR corrected p-value
GO:0005332gamma-aminobutyric acid:sodium symporter activity0.013582317476148
GO:0015185L-gamma-aminobutyric acid transmembrane transporter activity0.013582317476148
GO:0005283sodium:amino acid symporter activity0.013582317476148
GO:0005416cation:amino acid symporter activity0.013582317476148
GO:0005100Rho GTPase activator activity0.0183740213959862
GO:0005275amine transmembrane transporter activity0.0183740213959862
GO:0015179L-amino acid transmembrane transporter activity0.0183740213959862
GO:0005343organic acid:sodium symporter activity0.0183740213959862
GO:0005328neurotransmitter:sodium symporter activity0.0183740213959862
GO:0030308negative regulation of cell growth0.0183740213959862
GO:0005326neurotransmitter transporter activity0.0183740213959862
GO:0045792negative regulation of cell size0.0183740213959862
GO:0045926negative regulation of growth0.0183740213959862
GO:0015171amino acid transmembrane transporter activity0.0183740213959862
GO:0030155regulation of cell adhesion0.0183740213959862
GO:0006836neurotransmitter transport0.0203539814997523
GO:0015370solute:sodium symporter activity0.021609489514765
GO:0046943carboxylic acid transmembrane transporter activity0.0217481310394723
GO:0005342organic acid transmembrane transporter activity0.0217481310394723
GO:0015294solute:cation symporter activity0.0237858771763283
GO:0001558regulation of cell growth0.0312736747295867
GO:0005099Ras GTPase activator activity0.0312736747295867
GO:0016049cell growth0.0343385594509565
GO:0040008regulation of growth0.0343385594509565
GO:0008361regulation of cell size0.0343385594509565
GO:0015293symporter activity0.0387673400410537



Enriched sample ontology terms on this co-expression cluster
Summary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji



links to source dataset


uberon_data

disease_data

Uber Anatomy
Ontology termp-valuen
neural tube1.62e-1856
neural rod1.62e-1856
future spinal cord1.62e-1856
neural keel1.62e-1856
regional part of nervous system2.89e-1753
regional part of brain2.89e-1753
nervous system3.85e-1689
central nervous system9.40e-1681
brain5.29e-1568
future brain5.29e-1568
regional part of forebrain1.07e-1441
forebrain1.07e-1441
anterior neural tube1.07e-1441
future forebrain1.07e-1441
adult organism2.84e-14114
neurectoderm1.07e-1386
brain grey matter1.41e-1234
gray matter1.41e-1234
neural plate2.72e-1282
presumptive neural plate2.72e-1282
telencephalon1.37e-1134
regional part of telencephalon2.15e-1132
cerebral hemisphere5.77e-1132
ecto-epithelium1.83e-09104
regional part of cerebral cortex6.26e-0922
organ system subdivision8.36e-09223
ectoderm-derived structure8.96e-09171
ectoderm8.96e-09171
presumptive ectoderm8.96e-09171
pre-chordal neural plate6.47e-0861
cerebral cortex8.20e-0825
pallium8.20e-0825
neocortex9.54e-0820
neural nucleus9.74e-079
nucleus of brain9.74e-079
Disease
Ontology termp-valuen
disease of cellular proliferation2.07e-25239
cancer6.83e-25235
cell type cancer1.07e-12143
organ system cancer7.96e-12137
carcinoma4.15e-08106
hematologic cancer3.63e-0751
immune system cancer3.63e-0751


Overrepresented TFBS (DNA) motifs on this co-expression cluster
Summary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs

data

Novel motifs


JASPAR motifs
Motifs-log10(p-value)
MA0003.10
MA0004.12.3934e-05
MA0006.19.89923e-07
MA0007.11.3995e-05
MA0009.10.252275
MA0014.10
MA0017.13.65165e-07
MA0019.10.000628636
MA0024.10.00988067
MA0025.10.056119
MA0027.11.18893
MA0028.11.28676e-07
MA0029.10.0118495
MA0030.10.0106504
MA0031.10.00547833
MA0038.10.000270609
MA0040.10.0124978
MA0041.13.94674e-05
MA0042.11.63487e-05
MA0043.10.0240536
MA0046.10.0221119
MA0048.14.82164e-17
MA0050.11.6774e-05
MA0051.10.00024856
MA0052.10.0129401
MA0055.10
MA0056.10
MA0057.11.21023e-14
MA0058.11.02609e-06
MA0059.19.75558e-07
MA0060.12.51875e-11
MA0061.15.49785e-11
MA0063.10
MA0066.10.000272925
MA0067.10.129223
MA0068.11.21328e-09
MA0069.10.0214691
MA0070.10.0874332
MA0071.10.000118808
MA0072.10.0189844
MA0073.10
MA0074.10.000244797
MA0076.11.87499e-06
MA0077.10.017839
MA0078.10.00140868
MA0081.19.81798e-07
MA0083.10.0253592
MA0084.10.235205
MA0087.10.0186157
MA0088.10
MA0089.10
MA0090.14.041e-05
MA0091.12.57318e-05
MA0092.18.46866e-06
MA0093.16.85265e-08
MA0095.10
MA0098.10
MA0100.10.000355029
MA0101.18.06263e-08
MA0103.16.33078e-07
MA0105.10
MA0106.10.000587227
MA0107.12.41043e-08
MA0108.20.00529252
MA0109.10
MA0111.14.99406e-06
MA0113.10.000778799
MA0114.18.20707e-10
MA0115.10.094847
MA0116.11.46638e-09
MA0117.10.0313298
MA0119.15.09191e-07
MA0122.10.0371471
MA0124.10.0785459
MA0125.10.0508028
MA0130.10
MA0131.10.00183799
MA0132.10
MA0133.10
MA0135.10.856989
MA0136.10.000311127
MA0139.15.69773e-13
MA0140.10.000111852
MA0141.19.10947e-07
MA0142.10.00377456
MA0143.10.00078111
MA0144.12.95579e-10
MA0145.10
MA0146.10
MA0147.11.84684e-09
MA0148.14.65229e-05
MA0149.18.94152e-05
MA0062.21.18554e-12
MA0035.20.000110067
MA0039.20
MA0138.20.00143489
MA0002.22.92312e-09
MA0137.21.73869e-07
MA0104.22.35804e-11
MA0047.20.000472165
MA0112.20
MA0065.20
MA0150.12.55675e-06
MA0151.10
MA0152.10.000129708
MA0153.10.0460864
MA0154.10
MA0155.10
MA0156.11.92928e-07
MA0157.10.0026644
MA0158.10
MA0159.11.92515e-09
MA0160.16.8046e-05
MA0161.10
MA0162.10
MA0163.10
MA0164.10.00095582
MA0080.26.88208e-08
MA0018.20.000601703
MA0099.20.000130745
MA0079.20
MA0102.20.259495
MA0258.11.43431e-10
MA0259.13.16559e-09
MA0442.10


ENCODE TF ChIP-seq peak enrichment analysis
Summary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner



link to source dataset


data

No analysis results for this cluster

Relative expression of the co-expression cluster
Summary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data