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|full_id=C549_mesenchymal_Fibroblast_Synoviocyte_Hair_Smooth_Preadipocyte_Adipocyte
|full_id=C549_mesenchymal_Fibroblast_Synoviocyte_Hair_Smooth_Preadipocyte_Adipocyte
|id=C549
|id=C549
|ontology_enrichment_celltype=CL:0000055!1.27e-37!180;CL:0000048!4.63e-26!430;CL:0000723!2.00e-24!436;CL:0000222!4.48e-24!119;CL:0000034!1.86e-23!444;CL:0000057!2.90e-23!75;CL:0002371!6.18e-23!591;CL:0000144!4.57e-22!625;CL:0000680!4.86e-19!57;CL:0000056!4.86e-19!57;CL:0000355!4.86e-19!57;CL:0000187!1.28e-17!54;CL:0000183!3.78e-17!59;CL:0000393!6.70e-17!60;CL:0000211!6.70e-17!60;CL:0000012!1.06e-14!682;CL:0000548!1.12e-14!679;CL:0000004!1.12e-14!679;CL:0000255!1.12e-14!679;CL:0000192!4.32e-13!42;CL:0000514!4.32e-13!42;CL:0000359!2.71e-10!32;CL:0002320!5.17e-10!365;CL:0000134!6.54e-09!358;CL:0002139!2.75e-08!24;CL:0002057!4.26e-08!42;CL:0000220!8.35e-08!246;CL:0000213!1.13e-07!57;CL:0000215!1.13e-07!57;CL:0002494!1.47e-07!16;CL:0002321!1.77e-07!248;CL:0002620!1.78e-07!23;CL:0000219!2.41e-07!390;CL:0000115!3.25e-07!35;CL:0000003!6.77e-07!722;CL:0002334!9.45e-07!12
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0002049!1.71e-21!79;UBERON:0007798!1.71e-21!79;UBERON:0004872!9.39e-20!84;UBERON:0004535!1.09e-19!110;UBERON:0000914!1.59e-19!83;UBERON:0002329!1.59e-19!83;UBERON:0003077!1.59e-19!83;UBERON:0003059!1.59e-19!83;UBERON:0007282!1.59e-19!83;UBERON:0009618!1.59e-19!83;UBERON:0007285!1.59e-19!83;UBERON:0002204!2.40e-19!167;UBERON:0001009!2.54e-19!113;UBERON:0004290!2.99e-19!70;UBERON:0000055!7.24e-19!69;UBERON:0001134!8.45e-18!61;UBERON:0002036!8.45e-18!61;UBERON:0003082!8.45e-18!61;UBERON:0002385!4.31e-17!63;UBERON:0001015!4.31e-17!63;UBERON:0000383!4.31e-17!63;UBERON:0001981!2.26e-16!60;UBERON:0007500!2.26e-16!60;UBERON:0004537!2.26e-16!60;UBERON:0006965!2.26e-16!60;UBERON:0000486!3.64e-16!82;UBERON:0003081!1.26e-14!216;UBERON:0001637!1.43e-14!42;UBERON:0003509!1.43e-14!42;UBERON:0004572!1.43e-14!42;UBERON:0000926!1.88e-14!448;UBERON:0004120!1.88e-14!448;UBERON:0006603!1.88e-14!448;UBERON:0000468!3.84e-14!659;UBERON:0003914!1.30e-12!118;UBERON:0000467!4.15e-12!625;UBERON:0000480!8.27e-12!626;UBERON:0005256!1.13e-11!143;UBERON:0004573!7.66e-11!33;UBERON:0004571!7.66e-11!33;UBERON:0002384!2.21e-10!375;UBERON:0000490!2.42e-10!138;UBERON:0002100!5.67e-08!216;UBERON:0000479!8.24e-08!787;UBERON:0000923!1.13e-07!604;UBERON:0005291!1.13e-07!604;UBERON:0006598!1.13e-07!604;UBERON:0002532!1.13e-07!604;UBERON:0002050!1.17e-07!605;UBERON:0005423!1.17e-07!605;UBERON:0000947!1.37e-07!21;UBERON:0010191!1.37e-07!21;UBERON:0000948!1.66e-07!24;UBERON:0005498!1.66e-07!24;UBERON:0004140!1.66e-07!24;UBERON:0009881!1.66e-07!24;UBERON:0004141!1.66e-07!24;UBERON:0003084!1.66e-07!24;UBERON:0007005!1.66e-07!24;UBERON:0004139!1.66e-07!24;UBERON:0004291!1.66e-07!24;UBERON:0000922!2.58e-07!612;UBERON:0007100!6.48e-07!27
}}
}}

Revision as of 14:54, 21 May 2012


Full id: C549_mesenchymal_Fibroblast_Synoviocyte_Hair_Smooth_Preadipocyte_Adipocyte



Phase1 CAGE Peaks

Hg19::chr3:157154631..157154645,+p1@PTX3
Hg19::chr3:157155336..157155388,+p@chr3:157155336..157155388
+
Hg19::chr3:157155622..157155680,+p@chr3:157155622..157155680
+
Hg19::chr3:157160219..157160248,+p@chr3:157160219..157160248
+
Hg19::chr3:157160368..157160384,+p@chr3:157160368..157160384
+
Hg19::chr3:157160410..157160429,+p@chr3:157160410..157160429
+
Hg19::chr3:157160431..157160467,+p@chr3:157160431..157160467
+
Hg19::chr3:157160468..157160499,+p@chr3:157160468..157160499
+
Hg19::chr3:157160530..157160545,+p@chr3:157160530..157160545
+
Hg19::chr3:157160576..157160598,+p@chr3:157160576..157160598
+
Hg19::chr3:157160656..157160698,-p@chr3:157160656..157160698
-
Hg19::chr3:157160675..157160694,+p@chr3:157160675..157160694
+
Hg19::chr3:157160698..157160710,+p@chr3:157160698..157160710
+
Hg19::chr3:157160714..157160730,+p@chr3:157160714..157160730
+
Hg19::chr3:157160719..157160737,-p@chr3:157160719..157160737
-
Hg19::chr3:157160832..157160844,-p@chr3:157160832..157160844
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Hg19::chr3:157160884..157160892,-p@chr3:157160884..157160892
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
non-terminally differentiated cell1.27e-37180
multi fate stem cell4.63e-26430
somatic stem cell2.00e-24436
mesodermal cell4.48e-24119
stem cell1.86e-23444
fibroblast2.90e-2375
somatic cell6.18e-23591
muscle precursor cell4.86e-1957
myoblast4.86e-1957
multi-potent skeletal muscle stem cell4.86e-1957
muscle cell1.28e-1754
contractile cell3.78e-1759
electrically responsive cell6.70e-1760
electrically active cell6.70e-1760
animal cell1.12e-14679
eukaryotic cell1.12e-14679
smooth muscle cell4.32e-1342
smooth muscle myoblast4.32e-1342
vascular associated smooth muscle cell2.71e-1032
connective tissue cell5.17e-10365
mesenchymal cell6.54e-09358
endothelial cell of vascular tree2.75e-0824
CD14-positive, CD16-negative classical monocyte4.26e-0842
lining cell1.13e-0757
barrier cell1.13e-0757
cardiocyte1.47e-0716
embryonic cell1.77e-07248
skin fibroblast1.78e-0723
motile cell2.41e-07390
endothelial cell3.25e-0735
native cell6.77e-07722
preadipocyte9.45e-0712
Uber Anatomy
Ontology termp-valuen
vasculature1.71e-2179
vascular system1.71e-2179
splanchnic layer of lateral plate mesoderm9.39e-2084
cardiovascular system1.09e-19110
somite1.59e-1983
paraxial mesoderm1.59e-1983
presomitic mesoderm1.59e-1983
presumptive segmental plate1.59e-1983
trunk paraxial mesoderm1.59e-1983
presumptive paraxial mesoderm1.59e-1983
musculoskeletal system2.40e-19167
circulatory system2.54e-19113
dermomyotome2.99e-1970
vessel7.24e-1969
skeletal muscle tissue8.45e-1861
striated muscle tissue8.45e-1861
myotome8.45e-1861
muscle tissue4.31e-1763
musculature4.31e-1763
musculature of body4.31e-1763
blood vessel2.26e-1660
epithelial tube open at both ends2.26e-1660
blood vasculature2.26e-1660
vascular cord2.26e-1660
multilaminar epithelium3.64e-1682
lateral plate mesoderm1.26e-14216
artery1.43e-1442
arterial blood vessel1.43e-1442
arterial system1.43e-1442
mesoderm1.88e-14448
mesoderm-derived structure1.88e-14448
presumptive mesoderm1.88e-14448
multi-cellular organism3.84e-14659
epithelial tube1.30e-12118
anatomical system4.15e-12625
anatomical group8.27e-12626
trunk mesenchyme1.13e-11143
systemic artery7.66e-1133
systemic arterial system7.66e-1133
connective tissue2.21e-10375
unilaminar epithelium2.42e-10138
trunk5.67e-08216
tissue8.24e-08787
germ layer1.13e-07604
embryonic tissue1.13e-07604
presumptive structure1.13e-07604
epiblast (generic)1.13e-07604
embryonic structure1.17e-07605
developing anatomical structure1.17e-07605
aorta1.37e-0721
aortic system1.37e-0721
heart1.66e-0724
primitive heart tube1.66e-0724
primary heart field1.66e-0724
anterior lateral plate mesoderm1.66e-0724
heart tube1.66e-0724
heart primordium1.66e-0724
cardiac mesoderm1.66e-0724
cardiogenic plate1.66e-0724
heart rudiment1.66e-0724
embryo2.58e-07612
primary circulatory organ6.48e-0727


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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