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Coexpression cluster:C115

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Full id: C115_pituitary_Neural_caudate_putamen_amygdala_medulla_hippocampus



Phase1 CAGE Peaks

Hg19::chr10:106423509..106423521,+p@chr10:106423509..106423521
+
Hg19::chr10:123959529..123959547,+p@chr10:123959529..123959547
+
Hg19::chr10:18579999..18580012,-p@chr10:18579999..18580012
-
Hg19::chr10:18580030..18580043,-p@chr10:18580030..18580043
-
Hg19::chr10:18580125..18580134,+p@chr10:18580125..18580134
+
Hg19::chr10:18580138..18580153,+p@chr10:18580138..18580153
+
Hg19::chr11:111601666..111601697,-p@chr11:111601666..111601697
-
Hg19::chr11:68419276..68419303,-p@chr11:68419276..68419303
-
Hg19::chr11:9088284..9088330,-p4@SCUBE2
Hg19::chr12:113697781..113697814,+p7@TPCN1
Hg19::chr12:80603044..80603046,+p1@OTOGL
Hg19::chr12:89881337..89881342,-p@chr12:89881337..89881342
-
Hg19::chr12:89881348..89881356,-p@chr12:89881348..89881356
-
Hg19::chr13:40924577..40924587,-p2@ENST00000400432
Hg19::chr13:40924605..40924623,-p1@ENST00000400432
Hg19::chr13:51617751..51617754,+p@chr13:51617751..51617754
+
Hg19::chr14:62584108..62584133,+p1@FLJ43390
Hg19::chr14:62584173..62584178,+p2@ENST00000334389
Hg19::chr15:24157554..24157578,+p@chr15:24157554..24157578
+
Hg19::chr15:33445488..33445523,-p@chr15:33445488..33445523
-
Hg19::chr15:33445536..33445552,-p@chr15:33445536..33445552
-
Hg19::chr15:48681810..48681835,-p@chr15:48681810..48681835
-
Hg19::chr15:62352961..62352973,-p8@VPS13C
Hg19::chr15:89147906..89147920,+p@chr15:89147906..89147920
+
Hg19::chr16:21049173..21049231,-p@chr16:21049173..21049231
-
Hg19::chr17:18021982..18021985,+p3@MYO15A
Hg19::chr17:191188..191219,-p@chr17:191188..191219
-
Hg19::chr17:191225..191238,-p@chr17:191225..191238
-
Hg19::chr17:61995906..61995914,-p6@AB591020
Hg19::chr17:61995979..61995990,-p2@AB591020
Hg19::chr17:61995995..61996002,-p3@AB591020
Hg19::chr17:61996018..61996019,-p5@AB591020
Hg19::chr17:61996155..61996158,-p5@GH1
Hg19::chr17:61996160..61996176,-p3@GH1
Hg19::chr17:61996252..61996253,-p2@GH1
p3@CSHL1
Hg19::chr17:61996393..61996421,-p4@CSHL1
p4@GH1
Hg19::chr18:21824830..21824832,-p@chr18:21824830..21824832
-
Hg19::chr19:14095105..14095108,-p@chr19:14095105..14095108
-
Hg19::chr19:14946017..14946050,-p3@OR7A5
Hg19::chr19:2608406..2608413,-p@chr19:2608406..2608413
-
Hg19::chr19:46801484..46801498,+p9@HIF3A
Hg19::chr19:4770772..4770775,+p1@MIR7-3
Hg19::chr19:47793168..47793181,+p@chr19:47793168..47793181
+
Hg19::chr1:109656644..109656670,+p4@KIAA1324
Hg19::chr1:114483276..114483289,+p@chr1:114483276..114483289
+
Hg19::chr1:159116850..159116858,-p10@AIM2
Hg19::chr1:159116897..159116903,-p12@AIM2
Hg19::chr1:168250110..168250120,+p2@TBX19
Hg19::chr1:168250194..168250197,+p3@TBX19
Hg19::chr1:206942410..206942414,-p@chr1:206942410..206942414
-
Hg19::chr1:240286421..240286436,+p@chr1:240286421..240286436
+
Hg19::chr1:43400328..43400332,+p@chr1:43400328..43400332
+
Hg19::chr1:7709325..7709329,+p@chr1:7709325..7709329
+
Hg19::chr20:20505922..20505946,-p@chr20:20505922..20505946
-
Hg19::chr20:31667446..31667451,+p1@BPIFB4
Hg19::chr20:33451327..33451358,-p4@GGT7
Hg19::chr20:57415768..57415803,+p@chr20:57415768..57415803
+
Hg19::chr20:58401707..58401714,+p@chr20:58401707..58401714
+
Hg19::chr20:58401898..58401905,+p@chr20:58401898..58401905
+
Hg19::chr22:45015998..45016005,-p@chr22:45015998..45016005
-
Hg19::chr2:130941446..130941486,-p1@CU676019
Hg19::chr2:1714065..1714071,+p@chr2:1714065..1714071
+
Hg19::chr2:187287127..187287143,-p@chr2:187287127..187287143
-
Hg19::chr2:211830430..211830435,+p@chr2:211830430..211830435
+
Hg19::chr2:211830446..211830457,+p@chr2:211830446..211830457
+
Hg19::chr2:241080084..241080093,-p5@OTOS
Hg19::chr2:25383828..25383855,-p4@POMC
Hg19::chr2:25383910..25383918,-p17@POMC
Hg19::chr2:25383947..25383959,+p@chr2:25383947..25383959
+
Hg19::chr2:25391399..25391417,-p8@POMC
Hg19::chr2:25391425..25391439,-p10@POMC
Hg19::chr2:25391442..25391456,-p1@POMC
Hg19::chr2:25391468..25391485,-p5@POMC
Hg19::chr2:25391507..25391519,-p9@POMC
Hg19::chr2:25391657..25391666,-p14@POMC
Hg19::chr2:25391815..25391821,-p13@POMC
Hg19::chr2:45161466..45161475,+p@chr2:45161466..45161475
+
Hg19::chr2:58113353..58113375,-p@chr2:58113353..58113375
-
Hg19::chr2:58113386..58113399,-p@chr2:58113386..58113399
-
Hg19::chr2:58113402..58113415,-p@chr2:58113402..58113415
-
Hg19::chr2:58113422..58113431,-p@chr2:58113422..58113431
-
Hg19::chr2:70312872..70312889,-p23@PCBP1-AS1
Hg19::chr2:70312899..70312908,-p44@PCBP1-AS1
Hg19::chr2:7497646..7497649,+p@chr2:7497646..7497649
+
Hg19::chr2:98962912..98962924,+p2@CNGA3
Hg19::chr3:108321623..108321685,+p4@DZIP3
Hg19::chr3:114477881..114477914,-p17@ZBTB20
Hg19::chr3:118521917..118521922,-p@chr3:118521917..118521922
-
Hg19::chr3:130248877..130248886,+p@chr3:130248877..130248886
+
Hg19::chr3:130248915..130248922,+p@chr3:130248915..130248922
+
Hg19::chr3:130248948..130248959,+p@chr3:130248948..130248959
+
Hg19::chr3:133115455..133115457,+p@chr3:133115455..133115457
+
Hg19::chr3:154042775..154042780,-p8@DHX36
Hg19::chr3:185324217..185324224,+p1@ENST00000455173
Hg19::chr3:24206603..24206613,-p17@THRB
Hg19::chr3:24206934..24206942,-p24@THRB
Hg19::chr3:4774755..4774765,+p@chr3:4774755..4774765
+
Hg19::chr3:58572679..58572682,-p30@FAM107A
Hg19::chr3:58572689..58572703,-p6@FAM107A
Hg19::chr3:58572720..58572733,-p11@FAM107A
Hg19::chr3:58572734..58572746,-p8@FAM107A
Hg19::chr3:58572760..58572774,-p9@FAM107A
Hg19::chr3:79817089..79817094,-p27@ROBO1
Hg19::chr3:87325636..87325643,-p2@POU1F1
Hg19::chr3:87325728..87325739,-p1@POU1F1
Hg19::chr4:108815402..108815408,+p13@SGMS2
Hg19::chr4:1352813..1352818,-p@chr4:1352813..1352818
-
Hg19::chr4:6635531..6635534,+p@chr4:6635531..6635534
+
Hg19::chr4:70518941..70518967,-p1@UGT2A1
p1@UGT2A2
Hg19::chr4:76359403..76359419,-p1@ENST00000510744
Hg19::chr4:8103287..8103292,+p@chr4:8103287..8103292
+
Hg19::chr5:132668491..132668494,+p@chr5:132668491..132668494
+
Hg19::chr5:134509776..134509792,+p@chr5:134509776..134509792
+
Hg19::chr5:134509799..134509814,+p@chr5:134509799..134509814
+
Hg19::chr5:158737729..158737738,-p@chr5:158737729..158737738
-
Hg19::chr5:158737824..158737862,+p1@ENST00000521472
Hg19::chr5:165553564..165553568,-p@chr5:165553564..165553568
-
Hg19::chr5:77409743..77409752,-p6@AP3B1
Hg19::chr6:12717892..12717903,+p23@PHACTR1
Hg19::chr6:139155017..139155049,-p@chr6:139155017..139155049
-
Hg19::chr6:163149056..163149101,+p2@PACRG
Hg19::chr6:168333280..168333294,+p9@MLLT4
Hg19::chr6:22287516..22287522,-p@chr6:22287516..22287522
-
Hg19::chr6:22287527..22287538,-p@chr6:22287527..22287538
-
Hg19::chr6:22287619..22287636,-p@chr6:22287619..22287636
-
Hg19::chr6:22287669..22287676,-p@chr6:22287669..22287676
-
Hg19::chr6:22287695..22287700,-p@chr6:22287695..22287700
-
Hg19::chr6:22297257..22297272,-p1@PRL
Hg19::chr6:82727317..82727327,+p@chr6:82727317..82727327
+
Hg19::chr6:88805080..88805083,-p@chr6:88805080..88805083
-
Hg19::chr7:103549700..103549706,-p@chr7:103549700..103549706
-
Hg19::chr7:150644605..150644616,-p@chr7:150644605..150644616
-
Hg19::chr7:31003560..31003576,+p5@GHRHR
Hg19::chr7:31003580..31003589,+p6@GHRHR
Hg19::chr7:31006649..31006651,+p@chr7:31006649..31006651
+
Hg19::chr7:31009189..31009197,+p11@GHRHR
Hg19::chr7:31010569..31010576,+p9@GHRHR
Hg19::chr7:31010582..31010601,+p4@GHRHR
Hg19::chr7:31016265..31016282,+p@chr7:31016265..31016282
+
Hg19::chr7:95114742..95114776,+p4@ASB4
Hg19::chr8:1066886..1066919,+p@chr8:1066886..1066919
+
Hg19::chr8:107844170..107844179,+p@chr8:107844170..107844179
+
Hg19::chr8:130017368..130017390,+p@chr8:130017368..130017390
+
Hg19::chr9:135964996..135965001,+p@chr9:135964996..135965001
+
Hg19::chr9:135965121..135965124,+p@chr9:135965121..135965124
+
Hg19::chr9:547212..547233,+p28@KANK1
Hg19::chr9:75568126..75568136,-p13@ALDH1A1
Hg19::chr9:75568163..75568197,-p8@ALDH1A1
Hg19::chrX:111923145..111923173,-p1@LHFPL1
Hg19::chrX:130215591..130215605,+p@chrX:130215591..130215605
+
Hg19::chrX:130215610..130215625,+p@chrX:130215610..130215625
+
Hg19::chrX:130215640..130215656,+p@chrX:130215640..130215656
+
Hg19::chrX:130423240..130423288,-p1@IGSF1
Hg19::chrX:130423386..130423397,-p6@IGSF1
Hg19::chrX:147887590..147887594,+p@chrX:147887590..147887594
+
Hg19::chrX:150345054..150345060,+p1@GPR50
Hg19::chrX:24169518..24169522,+p8@ZFX
Hg19::chrX:38147077..38147085,-p@chrX:38147077..38147085
-
Hg19::chrX:38183144..38183165,-p@chrX:38183144..38183165
-
Hg19::chrX:9528518..9528536,+p@chrX:9528518..9528536
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


p.valueFDRnGenesnPathwayName
2.57139298499459e-050.01627691759501575272Neuroactive ligand-receptor interaction (KEGG):04080



Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0050954sensory perception of mechanical stimulus0.0393796071001252
GO:0007605sensory perception of sound0.0393796071001252
GO:0005515protein binding0.0393796071001252
GO:0032501multicellular organismal process0.0445827919264483
GO:0048187inhibin beta-B binding0.0445827919264483
GO:0031593polyubiquitin binding0.0445827919264483
GO:0005179hormone activity0.0445827919264483
GO:0007600sensory perception0.0445827919264483
GO:0051138positive regulation of NK T cell differentiation0.0445827919264483
GO:0033188sphingomyelin synthase activity0.0445827919264483
GO:0047493ceramide cholinephosphotransferase activity0.0445827919264483
GO:0048007antigen processing and presentation, exogenous lipid antigen via MHC class Ib0.0445827919264483
GO:0001865NK T cell differentiation0.0445827919264483
GO:0051136regulation of NK T cell differentiation0.0445827919264483
GO:0048186inhibin beta-A binding0.0445827919264483
GO:0005148prolactin receptor binding0.0445827919264483
GO:0048856anatomical structure development0.0445827919264483
GO:0003008system process0.0445827919264483
GO:0002475antigen processing and presentation via MHC class Ib0.0445827919264483
GO:0021984adenohypophysis development0.0445827919264483
GO:0001758retinal dehydrogenase activity0.0445827919264483
GO:0008046axon guidance receptor activity0.0445827919264483
GO:0006686sphingomyelin biosynthetic process0.0445827919264483
GO:0048003antigen processing and presentation of lipid antigen via MHC class Ib0.0445827919264483
GO:0003712transcription cofactor activity0.0445827919264483



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism4.72e-46115
neural tube2.87e-3157
neural rod2.87e-3157
future spinal cord2.87e-3157
neural keel2.87e-3157
central nervous system5.42e-3182
regional part of nervous system6.98e-3094
nervous system6.98e-3094
regional part of brain8.21e-2659
neural plate1.19e-2486
presumptive neural plate1.19e-2486
anterior neural tube1.64e-2442
brain1.77e-2469
future brain1.77e-2469
regional part of forebrain2.84e-2441
forebrain2.84e-2441
future forebrain2.84e-2441
neurectoderm1.71e-2390
gray matter3.36e-2034
brain grey matter3.36e-2034
telencephalon5.02e-2034
regional part of telencephalon2.04e-1933
cerebral hemisphere4.99e-1932
pre-chordal neural plate9.61e-1961
ectoderm-derived structure4.01e-17169
ectoderm1.08e-16173
presumptive ectoderm1.08e-16173
anterior region of body2.65e-16129
craniocervical region2.65e-16129
regional part of cerebral cortex6.28e-1522
cerebral cortex8.71e-1525
pallium8.71e-1525
head1.80e-14123
neocortex1.38e-1320
organ part6.49e-08219
posterior neural tube6.56e-0815
chordal neural plate6.56e-0815
nucleus of brain6.73e-079
basal ganglion6.73e-079
neural nucleus6.73e-079
nuclear complex of neuraxis6.73e-079
aggregate regional part of brain6.73e-079
collection of basal ganglia6.73e-079
cerebral subcortex6.73e-079
segmental subdivision of nervous system8.70e-0713


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data