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Coexpression cluster:C1659: Difference between revisions

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|ontology_enrichment_celltype=
|ontology_enrichment_celltype=
|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0001049!1.65e-60!57;UBERON:0005068!1.65e-60!57;UBERON:0006241!1.65e-60!57;UBERON:0007135!1.65e-60!57;UBERON:0001017!2.52e-58!82;UBERON:0005743!3.87e-57!86;UBERON:0002780!6.70e-57!41;UBERON:0001890!6.70e-57!41;UBERON:0006240!6.70e-57!41;UBERON:0002020!1.81e-55!34;UBERON:0003528!1.81e-55!34;UBERON:0003080!2.82e-55!42;UBERON:0001893!3.33e-55!34;UBERON:0000955!1.10e-53!69;UBERON:0006238!1.10e-53!69;UBERON:0002791!2.40e-53!33;UBERON:0002616!9.87e-53!59;UBERON:0001869!1.15e-52!32;UBERON:0000073!5.33e-52!94;UBERON:0001016!5.33e-52!94;UBERON:0003075!5.80e-51!86;UBERON:0007284!5.80e-51!86;UBERON:0002346!5.89e-48!90;UBERON:0000956!3.77e-44!25;UBERON:0000203!3.77e-44!25;UBERON:0003056!9.90e-41!61;UBERON:0002619!3.08e-39!22;UBERON:0001950!1.46e-35!20;UBERON:0000033!3.28e-33!123;UBERON:0007023!4.53e-32!115;UBERON:0000153!6.72e-31!129;UBERON:0007811!6.72e-31!129;UBERON:0004121!3.40e-29!169;UBERON:0000924!4.26e-28!173;UBERON:0006601!4.26e-28!173;UBERON:0000025!7.32e-13!194;UBERON:0000200!7.77e-13!6;UBERON:0002308!1.14e-12!9;UBERON:0000125!1.14e-12!9;UBERON:0001871!2.43e-12!7;UBERON:0001872!1.17e-10!5;UBERON:0002021!2.16e-10!5;UBERON:0002420!6.91e-10!9;UBERON:0007245!6.91e-10!9;UBERON:0010009!6.91e-10!9;UBERON:0010011!6.91e-10!9;UBERON:0000454!6.91e-10!9;UBERON:0000064!1.48e-09!219;UBERON:0009663!1.70e-09!7;UBERON:0004111!3.36e-09!241;UBERON:0003076!3.99e-08!15;UBERON:0003057!3.99e-08!15;UBERON:0000475!2.26e-07!365;UBERON:0002298!2.36e-07!8;UBERON:0002771!2.38e-07!3;UBERON:0000062!2.81e-07!511;UBERON:0000483!3.39e-07!309;UBERON:0000349!4.32e-07!5;UBERON:0000119!5.44e-07!312
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686325,0.0569043,0.0639461,0.387306,0.267408,0.312064,0.080156,0.274185,0.53753,0.0545112,0.510703,0.33844,0.0649137,0.0974216,0.595767,0.195675,0.174786,0.176557,0.396547,0.0472148,0.735114,0.229138,0.0639045,0.141461,0.0900204,0.228387,0.385962,0.334921,0.296227,0.208788,0.566117,0.36304,0.430936,0.123626,0.270619,0.132705,0.285556,0.493429,0.233835,0.224471,0.262929,0.223204,0.143824,0.460679,0.431098,0.0775891,0.153079,0.62577,0.211515,0.125701,0.175283,0.204954,0.209341,0.855975,0.629422,0.084895,0.160115,0.0819954,0.10091,0.122658,0.151161,0.228398,0.056055,0.120552,0.41771,0.893893,0.529713,0.335207,0.434016,0.190688,0.299739,0.278645,0.733648,0.0940982,0.0780533,0.564811,0.0993772,0.274769,0.448923,0.11602,0.344528,0.436413,0.0585992,0.20045,0.274438,0.98236,0.989834,0.319826,0.336512,0.173868,0.109708,0.174594,0.0809806,0.154589,0.318794,0.122767,0.0749261,0.176858,0.114361,0.347759,0.242462,0.0620267,0.211111,0.0738743,0.0882327,0.183058,0.150073,0.270522,0.16872,0.341388,0.0934526,0.359135,0.123404,0.430769,0.240825,0.3033,0.336623,0.163542,0.483244,0.27134,0.500871,0.239667,0.10226,0.29809,0.235147,0.689826,0.245965,0.116923,0.148426,0.0983658,0.228743,0.238223,0.156976,0.244789,0.267391,0.301441,0.21807,0.350528,0.382904,0.432408,0.190404,0.135865,0.488841,0.18137,0.180609,0.291283,0.273972,0.153023,0.400137,0.37958,0.22307,0.160699,0.391307,0.166736,0.181253,0.0422294,0.263877,0.146486,0.769574,0.262486,0.294204,0.131936,0.288826,0.246621,0.463617,0.697373,0.0965376,0.377203,0.279263,0.336564,0.35463,0.581771,0.800557,0.0594155,0.587524,0.208795,0.0713793,0.212621,0.594469,0.1798,0.629713,0.581874,0.355154,0.730614,0.619037,0.537088,0.603804,0.629445,0.306963,0.206759,0.526495,0.580285,0.550495,0.424482,0.820986,0.610475,0.881697,0.561689,0.102829,0.321844,0.623136,0.708698,0.96913,0.967174,0.349068,0.70429,0.798758,0.557035,0.427789,0.689998,0.737642,0.886619,0.433702,0.258394,0.644878,0.432123,0.759415,0.661773,0.494975,0.651196,0.392155,0.626931,0.371758,0.91821,0.562417,0.890566,0.85279,0.254547,0.901563,0.821811,0.680843,0.931136,0.541378,0.922893,0.660884,0.922144,0.898765,0.914902,0.315485,0.311289,0.318577,0.4488,0.389888,0.603509,0.161355,0.553178,0.246387,0.224252,0.0603905,0.155054,0.466978,0.518234,0.257848,0.353942,0.192234,0.427276,0.747776,0.466967,0.283682,0.424668,0.7175,0.797471,0.583101,0.702164,0.477016,0.831202,0.498956,0.465544,0.55798,0.708394,0.932831,0.723248,0.34194,0.592696,0.592314,0.644904,0.647996,0.763919,0.317485,0.633504,0.220564,0.845182,0.262394,0.307462,0.135076,0.469588,0.664443,0.274593,0.490712,0.541363,0.709432,0.583627,0.531474,0.720644,0.562305,0.174119,0.361524,0.31558,0.412744,0.54408,0.62698,0.513592,0.415367,0.503942,0.45585,0.36864,0.538745,0.456862,0.453004,0.680686,0.557093,0.330982,0.382214,0.553161,0.639572,0.68995,0.339393,0.694478,0.306231,0.298354,0.646049,0.784543,0.457741,0.641611,0.426239,0.748909,0.656093,0.572661,0.412586,0.534679,0.41502,0.55475,0.66153,0.523749,0.499347,0.307426,0.790204,0.557732,0.490527,0.714189,0.44799,0.813041,0.318338,0.276338,0.126433,0.417412,0.318174,0.0555558,0.295666,0.393022,0.293641,0.116969,0.401231,0.255983,0.297663,0.256708,0.338258,0.322052,0.145568,0.153833,0.261242,0.38389,0.54721,0.388459,0.321362,0.627637,0.280757,0.301366,0.340343,0.343265,0.501812,0.462092,0.336254,0.308589,0.291523,0.19697,0.309816,0.0537285,0.15063,0.198077,0.281455,0.348739,0.419895,0.138495,0.208834,0.32256,0.377566,0.342366,0.109684,0.322704,0.403482,0.181288,0.230841,0.352328,0.255358,0.351665,0.265112,0.0633313,0.10772,0.0854747,0.0747609,0.406458,0.312881,0.162482,0.244656,0.192188,0.158985,0.174153,0.0972854,0.333309,0.249919,0.339517,0.303699,0.198326,0.394084,0.126349,0.282501,0.252005,0.390891,0.238377,0.334983,0.197875,0.287909,0.289389,0.117618,0.392533,0.396962,0.316002,0.330317,0.321404,0.225079,0.300542,0.379651,0.185715,0.345505,0.375521,0.271405,0.311201,0.221943,0.306427,0.367733,0.246925,0.208775,0.390438,0.343014,0.270094,0.276922,0.156279,0.313647,0.461742,0.422872,0.336468,0.13327,0.313545,0.17149,0.0877361,0.0880065,0.238969,0.126615,0.0669467,0.0879453,0.474066,0.396935,0.326779,0.292869,0.358198,0.29552,0.131776,0.158116,0.104606,0.194814,0.104167,0.168186,0.108081,0.123829,0.205215,0.175247,0.0724304,0.109077,0.144842,0.0604892,0.214671,0.316879,0.442567,0.430541,0.508546,0.224871,0.398887,0.389061,0.310732,0.349611,0.445995,0.385709,0.278202,0.426488,0.400591,0.209809,0.253154,0.319519,0.309489,0.430805,0.362154,0.480785,0.185476,0.336314,0.344469,0.184651,0.303359,0.297596,0.42392,0.425912,0.380826,0.259046,0.345068,0.151046,0.142558,0.347171,0.321735,0.15463,0.13907,0.470121,0.269432,0.250466,0.409882,0.115686,0.408975,0.162633,0.342661,0.27567,0.248127,0.33299,0.384731,0.319112,0.526476
}}
}}

Revision as of 11:33, 19 October 2012


Full id: C1659_pineal_occipital_middle_parietal_medial_brain_olfactory



Phase1 CAGE Peaks

Hg19::chr12:121085388..121085391,+p@chr12:121085388..121085391
+
Hg19::chr12:121095913..121095917,+p@chr12:121095913..121095917
+
Hg19::chr12:130303267..130303284,-p@chr12:130303267..130303284
-
Hg19::chr12:130313403..130313404,-p@chr12:130313403..130313404
-
Hg19::chr7:39299516..39299530,+p@chr7:39299516..39299530
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
regional part of nervous system5.65e-8253
regional part of brain5.65e-8253
neural tube1.95e-7756
neural rod1.95e-7756
future spinal cord1.95e-7756
neural keel1.95e-7756
regional part of forebrain5.09e-7641
forebrain5.09e-7641
anterior neural tube5.09e-7641
future forebrain5.09e-7641
brain grey matter2.56e-7534
gray matter2.56e-7534
cerebral hemisphere2.31e-7232
telencephalon5.02e-6834
brain1.57e-6768
future brain1.57e-6768
regional part of cerebral cortex1.51e-6522
regional part of telencephalon8.96e-6532
neocortex1.29e-6220
cerebral cortex1.17e-5725
pallium1.17e-5725
central nervous system2.85e-5681
neural plate4.62e-5682
presumptive neural plate4.62e-5682
pre-chordal neural plate5.51e-5561
neurectoderm2.78e-5386
nervous system2.45e-5089
ecto-epithelium2.16e-43104
adult organism6.03e-43114
gyrus2.05e-416
structure with developmental contribution from neural crest3.51e-36132
ectoderm-derived structure1.37e-26171
ectoderm1.37e-26171
presumptive ectoderm1.37e-26171
parietal lobe2.00e-225
frontal cortex5.02e-223
tube9.82e-20192
organ system subdivision2.28e-19223
neural nucleus1.25e-189
nucleus of brain1.25e-189
regional part of diencephalon2.38e-164
temporal lobe2.62e-166
corpus striatum7.44e-164
striatum7.44e-164
ventral part of telencephalon7.44e-164
future corpus striatum7.44e-164
pineal body2.05e-152
middle frontal gyrus2.05e-152
regional part of epithalamus2.05e-152
secretory circumventricular organ2.05e-152
circumventricular organ2.05e-152
epithalamus2.05e-152
middle temporal gyrus3.88e-152
anatomical conduit6.98e-15240
locus ceruleus1.93e-142
brainstem nucleus1.93e-142
hindbrain nucleus1.93e-142
organ part9.12e-14218
limbic system2.67e-135
basal ganglion1.84e-129
nuclear complex of neuraxis1.84e-129
aggregate regional part of brain1.84e-129
collection of basal ganglia1.84e-129
cerebral subcortex1.84e-129
epithelium8.69e-12306
cell layer1.26e-11309
multi-tissue structure4.24e-11342
anatomical cluster9.12e-11373
brainstem1.23e-106
pons6.22e-103
caudate-putamen6.22e-103
dorsal striatum6.22e-103
diencephalon1.45e-097
future diencephalon1.45e-097
telencephalic nucleus2.74e-097
segmental subdivision of hindbrain4.07e-0912
hindbrain4.07e-0912
presumptive hindbrain4.07e-0912
olfactory region1.75e-081
primary subdivision of skull1.75e-081
cranium1.75e-081
neurocranium1.75e-081
chondrocranium1.75e-081
cartilaginous neurocranium1.75e-081
head paraxial mesoderm1.75e-081
segmental subdivision of nervous system2.00e-0813
insula2.50e-081
paracentral gyrus2.69e-081
occipital pole2.89e-081
pole of cerebral hemisphere2.89e-081
nucleus accumbens3.10e-081
ventral striatum3.10e-081
gland of diencephalon3.84e-084
neuroendocrine gland3.84e-084
putamen4.11e-081
postcentral gyrus7.16e-081
posterior neural tube2.55e-0715
chordal neural plate2.55e-0715
regional part of metencephalon3.05e-079
metencephalon3.05e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.