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MCL coexpression mm9:763

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:42303385..42303401,-p1@Nr2e1
Mm9::chr10:42303410..42303422,-p3@Nr2e1
Mm9::chr10:42303434..42303445,-p4@Nr2e1
Mm9::chr10:42303452..42303470,-p2@Nr2e1
Mm9::chr10:42303593..42303617,+p3@Ostm1
Mm9::chr13:100214377..100214396,-p5@Mtap1b
Mm9::chr13:100214398..100214443,-p4@Mtap1b
Mm9::chr15:30387382..30387465,+p@chr15:30387382..30387465
+
Mm9::chr4:154335024..154335039,+p1@Hes5


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0045665negative regulation of neuron differentiation0.000794495253785691
GO:0045664regulation of neuron differentiation0.000838742615128936
GO:0030182neuron differentiation0.000838742615128936
GO:0048699generation of neurons0.00091378028845023
GO:0022008neurogenesis0.00091378028845023
GO:0048731system development0.00163346912530473
GO:0048869cellular developmental process0.00163346912530473
GO:0030154cell differentiation0.00163346912530473
GO:0048856anatomical structure development0.00235172011241831
GO:0045596negative regulation of cell differentiation0.00235172011241831
GO:0007399nervous system development0.00251666452717617
GO:0045165cell fate commitment0.00251666452717617
GO:0007275multicellular organismal development0.00251666452717617
GO:0051093negative regulation of developmental process0.00251666452717617
GO:0021960anterior commissure morphogenesis0.00268814258843295
GO:0045595regulation of cell differentiation0.00476361711834936
GO:0032502developmental process0.00537390981097135
GO:0007423sensory organ development0.00537390981097135
GO:0021988olfactory lobe development0.00537390981097135
GO:0042668auditory receptor cell fate determination0.00537390981097135
GO:0021772olfactory bulb development0.00537390981097135
GO:0008347glial cell migration0.00537390981097135
GO:0031175neurite development0.00537390981097135
GO:0048666neuron development0.00625326153862338
GO:0048468cell development0.00625326153862338
GO:0060120inner ear receptor cell fate commitment0.00719801520321865
GO:0009912auditory receptor cell fate commitment0.00719801520321865
GO:0021952central nervous system projection neuron axonogenesis0.00719801520321865
GO:0050793regulation of developmental process0.00721312630204343
GO:0032990cell part morphogenesis0.00721312630204343
GO:0048858cell projection morphogenesis0.00721312630204343
GO:0030030cell projection organization and biogenesis0.00721312630204343
GO:0048513organ development0.00801501860859627
GO:0005519cytoskeletal regulatory protein binding0.00829752406539178
GO:0021987cerebral cortex development0.00895532164740805
GO:0035176social behavior0.00895532164740805
GO:0001578microtubule bundle formation0.00915266077810837
GO:0060041retina development in camera-type eye0.00915266077810837
GO:0021955central nervous system neuron axonogenesis0.00915266077810837
GO:0005829cytosol0.00915266077810837
GO:0032501multicellular organismal process0.00988022014933451
GO:0021543pallium development0.0131141185809079
GO:0016439tRNA-pseudouridine synthase activity0.0131141185809079
GO:0000902cell morphogenesis0.0150329301666908
GO:0032989cellular structure morphogenesis0.0150329301666908
GO:0009982pseudouridine synthase activity0.0157561972414516
GO:0030316osteoclast differentiation0.0171315822530225
GO:0021954central nervous system neuron development0.0176119602344722
GO:0051705behavioral interaction between organisms0.0180725959911146
GO:0042491auditory receptor cell differentiation0.0181516412460269
GO:0021537telencephalon development0.0181516412460269
GO:0021953central nervous system neuron differentiation0.0182245960741205
GO:0001709cell fate determination0.0182245960741205
GO:0060113inner ear receptor cell differentiation0.0201180295317525
GO:0016866intramolecular transferase activity0.0212118888217189
GO:0042490mechanoreceptor differentiation0.0236988425884903
GO:0016358dendrite development0.0275027898001106
GO:0002573myeloid leukocyte differentiation0.0277193658618234
GO:0042063gliogenesis0.0279284885099959
GO:0005496steroid binding0.0309506211559055
GO:0003707steroid hormone receptor activity0.0309506211559055
GO:0004879ligand-dependent nuclear receptor activity0.031096763193158
GO:0048523negative regulation of cellular process0.0330922663318068
GO:0048519negative regulation of biological process0.037446062826476
GO:0000226microtubule cytoskeleton organization and biogenesis0.039496706719972
GO:0048839inner ear development0.0425239977973949
GO:0048469cell maturation0.0441397823276559
GO:0043010camera-type eye development0.0441397823276559
GO:0043583ear development0.0441397823276559



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
CNS neuron (sensu Vertebrata)6.92e-0923
neuroblast (sensu Vertebrata)6.92e-0923
ectodermal cell2.56e-0844
neurectodermal cell2.56e-0844
neuron of cerebral cortex3.86e-086
neural cell1.19e-0743

Uber Anatomy
Ontology termp-valuen
pre-chordal neural plate4.78e-3449
anterior neural tube2.26e-2440
neurectoderm5.14e-2464
neural plate5.14e-2464
presumptive neural plate5.14e-2464
regional part of forebrain1.04e-2339
forebrain1.04e-2339
future forebrain1.04e-2339
brain grey matter3.54e-2329
regional part of telencephalon3.54e-2329
telencephalon3.54e-2329
brain4.24e-2247
future brain4.24e-2247
ectoderm-derived structure4.62e-2295
ectoderm4.62e-2295
presumptive ectoderm4.62e-2295
ecto-epithelium1.29e-2173
regional part of brain2.58e-2146
central nervous system1.11e-1873
regional part of nervous system1.51e-1854
gray matter2.62e-1834
cerebral cortex3.13e-1821
cerebral hemisphere3.13e-1821
pallium3.13e-1821
nervous system8.75e-1875
neural tube1.92e-1752
neural rod1.92e-1752
future spinal cord1.92e-1752
neural keel1.92e-1752
regional part of cerebral cortex5.58e-1417
structure with developmental contribution from neural crest5.77e-1492
sense organ1.19e-1012
sensory system1.19e-1012
entire sense organ system1.19e-1012
eye1.73e-109
camera-type eye1.73e-109
simple eye1.73e-109
immature eye1.73e-109
ocular region1.73e-109
visual system1.73e-109
face1.73e-109
optic cup1.73e-109
optic vesicle1.73e-109
eye primordium1.73e-109
head1.48e-0913
ectodermal placode1.48e-0913
subdivision of head4.53e-0811
occipital lobe6.09e-0810
visual cortex6.09e-0810
neocortex6.09e-0810
Ammon's horn1.53e-077
lobe parts of cerebral cortex1.53e-077
hippocampal formation1.53e-077
limbic system1.53e-077
limbic lobe1.53e-077


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.11.84202
MA0004.10.394951
MA0006.12.71192
MA0007.10.991467
MA0009.10.82278
MA0014.10.433479
MA0017.10.26239
MA0019.10.642876
MA0024.10.779446
MA0025.11.05446
MA0027.12.46647
MA0028.10.24786
MA0029.10.757957
MA0030.10.764448
MA0031.10.729293
MA0038.10.534262
MA0040.10.835181
MA0041.10.323687
MA0042.10.311486
MA0043.10.918718
MA0046.10.858391
MA0048.11.47862
MA0050.11.10321
MA0051.10.542972
MA0052.10.84317
MA0055.10.0198867
MA0056.10
MA0057.11.39929
MA0058.10.305206
MA0059.10.316585
MA0060.10.9744
MA0061.10.194456
MA0063.10
MA0066.10.523573
MA0067.11.16502
MA0068.10.077274
MA0069.10.843506
MA0070.10.833895
MA0071.10.431174
MA0072.10.825495
MA0073.10.00108891
MA0074.10.488775
MA0076.10.279739
MA0077.10.804033
MA0078.11.40897
MA0081.10.338098
MA0083.10.917931
MA0084.11.49188
MA0087.10.87515
MA0088.10.18495
MA0089.10
MA0090.10.362551
MA0091.10.407455
MA0092.10.362847
MA0093.10.2553
MA0095.10
MA0098.10
MA0100.10.477594
MA0101.10.324888
MA0103.10.272167
MA0105.10.109964
MA0106.10.582805
MA0107.10.266586
MA0108.21.59789
MA0109.10
MA0111.10.375908
MA0113.10.555251
MA0114.10.19245
MA0115.10.921497
MA0116.10.238371
MA0117.12.06044
MA0119.10.325434
MA0122.12.10074
MA0124.11.11203
MA0125.11.03833
MA0130.10
MA0131.10.638414
MA0132.10
MA0133.10
MA0135.10.954884
MA0136.10.508047
MA0139.10.143341
MA0140.10.477483
MA0141.10.29014
MA0142.11.70108
MA0143.13.50871
MA0144.10.568165
MA0145.10.200183
MA0146.10.0548413
MA0147.11.75741
MA0148.10.410398
MA0149.10.330018
MA0062.20.113962
MA0035.20.482026
MA0039.20.175249
MA0138.20.630612
MA0002.20.145685
MA0137.20.783415
MA0104.22.12419
MA0047.20.533516
MA0112.20.0543294
MA0065.20.44341
MA0150.10.380623
MA0151.10
MA0152.10.53362
MA0153.10.971406
MA0154.10.0809407
MA0155.10.0631765
MA0156.10.278949
MA0157.10.683365
MA0158.10
MA0159.10.214506
MA0160.10.413266
MA0161.10
MA0162.10.348617
MA0163.10.0124565
MA0164.10.508398
MA0080.20.267388
MA0018.24.41766
MA0099.20.624421
MA0079.20.253208
MA0102.21.5442
MA0258.10.180934
MA0259.10.571417
MA0442.10
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