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Coexpression cluster:C1406

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Full id: C1406_cerebellum_pineal_occipital_parietal_middle_medial_Hepatocyte



Phase1 CAGE Peaks

Hg19::chr15:61364011..61364017,-p@chr15:61364011..61364017
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Hg19::chr15:61364032..61364045,-p@chr15:61364032..61364045
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Hg19::chr15:61364061..61364074,-p@chr15:61364061..61364074
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Hg19::chr3:10407562..10407571,-p@chr3:10407562..10407571
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Hg19::chr8:10220860..10220863,+p@chr8:10220860..10220863
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Hg19::chr8:10972308..10972348,-p@chr8:10972308..10972348
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube2.11e-5256
neural rod2.11e-5256
future spinal cord2.11e-5256
neural keel2.11e-5256
adult organism2.41e-50114
regional part of nervous system5.46e-4953
regional part of brain5.46e-4953
neurectoderm3.66e-4486
brain5.59e-4368
future brain5.59e-4368
regional part of forebrain4.23e-4241
forebrain4.23e-4241
anterior neural tube4.23e-4241
future forebrain4.23e-4241
neural plate6.32e-4282
presumptive neural plate6.32e-4282
central nervous system1.54e-4181
nervous system1.87e-3889
brain grey matter6.46e-3734
gray matter6.46e-3734
telencephalon2.37e-3634
regional part of telencephalon2.56e-3232
cerebral hemisphere3.04e-3232
ecto-epithelium7.72e-31104
pre-chordal neural plate1.77e-3061
structure with developmental contribution from neural crest1.71e-26132
regional part of cerebral cortex5.55e-2422
neocortex6.97e-2320
ectoderm-derived structure8.18e-21171
ectoderm8.18e-21171
presumptive ectoderm8.18e-21171
cerebral cortex9.40e-2125
pallium9.40e-2125
neural nucleus1.77e-199
nucleus of brain1.77e-199
organ system subdivision5.70e-18223
tube1.01e-15192
basal ganglion6.85e-159
nuclear complex of neuraxis6.85e-159
aggregate regional part of brain6.85e-159
collection of basal ganglia6.85e-159
cerebral subcortex6.85e-159
telencephalic nucleus2.75e-147
anatomical conduit6.14e-12240
corpus striatum9.42e-124
striatum9.42e-124
ventral part of telencephalon9.42e-124
future corpus striatum9.42e-124
gyrus9.78e-126
anatomical cluster1.99e-11373
posterior neural tube2.45e-1115
chordal neural plate2.45e-1115
caudate-putamen1.91e-093
dorsal striatum1.91e-093
occipital lobe5.52e-095
epithelium7.60e-09306
cell layer1.19e-08309
organ part1.90e-08218
multi-tissue structure2.01e-08342
segmental subdivision of hindbrain2.53e-0812
hindbrain2.53e-0812
presumptive hindbrain2.53e-0812
brainstem5.75e-086
regional part of diencephalon1.28e-074
segmental subdivision of nervous system1.28e-0713
gland of diencephalon2.04e-074
neuroendocrine gland2.04e-074
pineal body2.55e-072
regional part of epithalamus2.55e-072
secretory circumventricular organ2.55e-072
circumventricular organ2.55e-072
epithalamus2.55e-072
germ layer3.89e-07560
germ layer / neural crest3.89e-07560
embryonic tissue3.89e-07560
presumptive structure3.89e-07560
germ layer / neural crest derived structure3.89e-07560
epiblast (generic)3.89e-07560
diencephalon4.13e-077
future diencephalon4.13e-077
locus ceruleus5.29e-072
brainstem nucleus5.29e-072
hindbrain nucleus5.29e-072
embryonic structure5.61e-07564
middle temporal gyrus5.77e-072
caudate nucleus5.93e-072
future caudate nucleus5.93e-072
developing anatomical structure6.95e-07581
organ7.01e-07503


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.00461978
MA0004.10.558729
MA0006.10.391183
MA0007.10.539222
MA0009.11.03681
MA0014.10.0254709
MA0017.10.432438
MA0019.10.7124
MA0024.10.929647
MA0025.11.17262
MA0027.12.65688
MA0028.10.408079
MA0029.12.18297
MA0030.10.937696
MA0031.10.871496
MA0038.10.665566
MA0040.10.955415
MA0041.10.578072
MA0042.10.544748
MA0043.11.03713
MA0046.11.02569
MA0048.10.152639
MA0050.11.34656
MA0051.10.661179
MA0052.10.959373
MA0055.10.0586456
MA0056.10
MA0057.10.147053
MA0058.10.458909
MA0059.10.457555
MA0060.10.267412
MA0061.10.671725
MA0063.10
MA0066.10.66601
MA0067.11.35893
MA0068.10.199491
MA0069.11.02175
MA0070.11.01032
MA0071.10.625297
MA0072.11.00572
MA0073.10.959858
MA0074.10.660398
MA0076.10.475586
MA0077.10.997832
MA0078.10.763954
MA0081.10.457725
MA0083.11.04447
MA0084.11.5477
MA0087.11.00322
MA0088.10.32124
MA0089.10
MA0090.10.490736
MA0091.10.561458
MA0092.10.522012
MA0093.10.394379
MA0095.10
MA0098.10
MA0100.10.679972
MA0101.10.397846
MA0103.10.381434
MA0105.10.419295
MA0106.10.70837
MA0107.10.857383
MA0108.20.868347
MA0109.10
MA0111.10.504913
MA0113.11.72264
MA0114.10.314898
MA0115.11.28169
MA0116.10.323925
MA0117.11.07516
MA0119.11.96285
MA0122.11.10154
MA0124.11.23968
MA0125.11.15445
MA0130.10
MA0131.10.782708
MA0132.10
MA0133.10
MA0135.11.06778
MA0136.10.672893
MA0139.10.226048
MA0140.10.622527
MA0141.10.455728
MA0142.10.838805
MA0143.10.725558
MA0144.10.299851
MA0145.10.107156
MA0146.10.0213085
MA0147.10.327615
MA0148.10.584698
MA0149.10.612449
MA0062.20.23336
MA0035.21.50688
MA0039.20.0929059
MA0138.20.765223
MA0002.20.255126
MA0137.20.414885
MA0104.20.26661
MA0047.20.695777
MA0112.20.101413
MA0065.20.109623
MA0150.10.484557
MA0151.10
MA0152.10.629368
MA0153.11.13732
MA0154.10.132326
MA0155.10.0961854
MA0156.10.417278
MA0157.11.89858
MA0158.10
MA0159.10.328286
MA0160.10.600559
MA0161.10
MA0162.10.0383129
MA0163.10.0270301
MA0164.10.738243
MA0080.20.394469
MA0018.20.709805
MA0099.20.629739
MA0079.25.9246e-06
MA0102.21.58513
MA0258.10.289793
MA0259.10.336472
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.