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Coexpression cluster:C2149

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Full id: C2149_Pericytes_spinal_kidney_cerebral_temporal_duodenum_retina



Phase1 CAGE Peaks

  Short description
Hg19::chr11:62752220..62752231,- p4@SLC22A6
Hg19::chr11:62752254..62752272,- p2@SLC22A6
Hg19::chr11:62752284..62752304,- p3@SLC22A6
Hg19::chr11:62752310..62752313,- p7@SLC22A6


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


No GOStat results

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data


Cell Type
Ontology termp-valuen
central nervous system pericyte3.64e-092
Uber Anatomy
Ontology termp-valuen
neural tube2.72e-10756
neural rod2.72e-10756
future spinal cord2.72e-10756
neural keel2.72e-10756
regional part of nervous system5.86e-9753
regional part of brain5.86e-9753
central nervous system2.82e-8681
brain7.07e-8168
future brain7.07e-8168
nervous system7.98e-7789
neural plate1.88e-7482
presumptive neural plate1.88e-7482
regional part of forebrain2.77e-7341
forebrain2.77e-7341
anterior neural tube2.77e-7341
future forebrain2.77e-7341
neurectoderm1.44e-7086
brain grey matter5.81e-6234
gray matter5.81e-6234
telencephalon2.18e-6134
ecto-epithelium9.59e-57104
cerebral hemisphere1.33e-5532
regional part of telencephalon2.46e-5532
adult organism2.26e-54114
pre-chordal neural plate9.88e-5161
structure with developmental contribution from neural crest1.97e-47132
regional part of cerebral cortex2.03e-4022
neocortex3.01e-3920
ectoderm-derived structure1.05e-37171
ectoderm1.05e-37171
presumptive ectoderm1.05e-37171
cerebral cortex2.88e-3525
pallium2.88e-3525
posterior neural tube1.38e-3315
chordal neural plate1.38e-3315
neural nucleus1.61e-309
nucleus of brain1.61e-309
basal ganglion1.98e-299
nuclear complex of neuraxis1.98e-299
aggregate regional part of brain1.98e-299
collection of basal ganglia1.98e-299
cerebral subcortex1.98e-299
organ system subdivision6.27e-28223
tube1.10e-24192
segmental subdivision of hindbrain1.14e-2312
hindbrain1.14e-2312
presumptive hindbrain1.14e-2312
telencephalic nucleus2.05e-237
brainstem7.69e-236
segmental subdivision of nervous system1.02e-2113
anatomical conduit8.51e-18240
anatomical cluster2.15e-15373
regional part of metencephalon3.05e-149
metencephalon3.05e-149
future metencephalon3.05e-149
corpus striatum4.20e-144
striatum4.20e-144
ventral part of telencephalon4.20e-144
future corpus striatum4.20e-144
diencephalon6.67e-137
future diencephalon6.67e-137
epithelium8.60e-13306
cell layer1.43e-12309
temporal lobe1.57e-126
pons2.12e-123
spinal cord3.09e-123
dorsal region element3.09e-123
dorsum3.09e-123
medulla oblongata3.45e-123
myelencephalon3.45e-123
future myelencephalon3.45e-123
occipital lobe8.27e-125
organ part1.27e-11218
parietal lobe1.42e-115
limbic system1.73e-115
multi-tissue structure3.40e-11342
caudate-putamen6.77e-113
dorsal striatum6.77e-113
gyrus1.99e-096
regional part of diencephalon7.12e-094
locus ceruleus7.58e-092
brainstem nucleus7.58e-092
hindbrain nucleus7.58e-092
meninx7.87e-092
membrane organ7.87e-092
meningeal cluster7.87e-092
organ1.45e-08503
dorsal plus ventral thalamus2.01e-082
thalamic complex2.01e-082
globus pallidus4.51e-082
pallidum4.51e-082
caudate nucleus8.58e-082
future caudate nucleus8.58e-082
amygdala1.02e-072


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.233555
MA0004.10.71247
MA0006.10.532262
MA0007.10.6918
MA0009.11.20602
MA0014.10.0695829
MA0017.11.41335
MA0019.10.873355
MA0024.11.09684
MA0025.11.34373
MA0027.12.83281
MA0028.10.550763
MA0029.11.11704
MA0030.11.10506
MA0031.11.03735
MA0038.10.824639
MA0040.11.12314
MA0041.10.732902
MA0042.10.697662
MA0043.11.20635
MA0046.11.19471
MA0048.12.82503
MA0050.10.69864
MA0051.10.820063
MA0052.11.12718
MA0055.11.28887
MA0056.10
MA0057.10.248209
MA0058.10.605914
MA0059.10.604454
MA0060.10.393285
MA0061.10.360128
MA0063.10
MA0066.10.825101
MA0067.11.53181
MA0068.10.313194
MA0069.11.19071
MA0070.11.17908
MA0071.10.782546
MA0072.11.1744
MA0073.10.00636811
MA0074.10.819248
MA0076.10.623864
MA0077.11.16637
MA0078.10.926725
MA0081.10.604638
MA0083.11.21381
MA0084.11.72172
MA0087.11.17185
MA0088.10.182167
MA0089.10
MA0090.10.640115
MA0091.10.715356
MA0092.10.673508
MA0093.10.535768
MA0095.10
MA0098.10
MA0100.10.83965
MA0101.10.539569
MA0103.10.521546
MA0105.10.232357
MA0106.10.869173
MA0107.10.453492
MA0108.21.03412
MA0109.10
MA0111.10.655276
MA0113.10.886811
MA0114.10.447443
MA0115.11.45393
MA0116.10.457606
MA0117.11.24497
MA0119.10.586221
MA0122.11.27173
MA0124.11.41151
MA0125.11.32534
MA0130.10
MA0131.10.94608
MA0132.10
MA0133.10
MA0135.11.23748
MA0136.10.832277
MA0139.10.344952
MA0140.10.779643
MA0141.10.602484
MA0142.11.00381
MA0143.10.887001
MA0144.10.430413
MA0145.11.08195
MA0146.11.25938
MA0147.10.46175
MA0148.10.739888
MA0149.10.769072
MA0062.20.353589
MA0035.20.778873
MA0039.20.0247757
MA0138.20.928035
MA0002.20.379056
MA0137.20.558189
MA0104.20.392359
MA0047.20.856092
MA0112.21.65877
MA0065.20.199162
MA0150.10.633493
MA0151.10
MA0152.10.78681
MA0153.11.30799
MA0154.10.229241
MA0155.10.533581
MA0156.10.560797
MA0157.10.97481
MA0158.10
MA0159.10.462502
MA0160.10.756582
MA0161.10
MA0162.10.0928415
MA0163.10.0725493
MA0164.10.90014
MA0080.20.535868
MA0018.20.870662
MA0099.20.7872
MA0079.20.0021048
MA0102.21.75932
MA0258.11.07498
MA0259.10.471671
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


No analysis results for this cluster

Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.