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Coexpression cluster:C3082

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Full id: C3082_parietal_pineal_temporal_occipital_hippocampus_middle_amygdala



Phase1 CAGE Peaks

Hg19::chr11:113146130..113146180,+p@chr11:113146130..113146180
+
Hg19::chr5:166996114..166996115,+p@chr5:166996114..166996115
+
Hg19::chr6:161186211..161186236,-p@chr6:161186211..161186236
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube4.40e-8356
neural rod4.40e-8356
future spinal cord4.40e-8356
neural keel4.40e-8356
regional part of nervous system1.83e-7753
regional part of brain1.83e-7753
regional part of forebrain3.60e-7141
forebrain3.60e-7141
anterior neural tube3.60e-7141
future forebrain3.60e-7141
central nervous system9.55e-7181
nervous system4.61e-6489
brain7.94e-6468
future brain7.94e-6468
neural plate1.03e-6282
presumptive neural plate1.03e-6282
neurectoderm3.91e-6186
brain grey matter3.82e-5934
gray matter3.82e-5934
telencephalon1.33e-5834
cerebral hemisphere6.33e-5632
regional part of telencephalon1.29e-5532
pre-chordal neural plate1.86e-5061
adult organism2.25e-48114
ecto-epithelium1.76e-47104
cerebral cortex1.48e-4325
pallium1.48e-4325
regional part of cerebral cortex7.11e-4322
structure with developmental contribution from neural crest7.91e-40132
neocortex4.55e-3920
ectoderm-derived structure2.98e-34171
ectoderm2.98e-34171
presumptive ectoderm2.98e-34171
organ system subdivision2.81e-25223
tube1.33e-20192
basal ganglion5.50e-179
nuclear complex of neuraxis5.50e-179
aggregate regional part of brain5.50e-179
collection of basal ganglia5.50e-179
cerebral subcortex5.50e-179
neural nucleus1.10e-169
nucleus of brain1.10e-169
anatomical cluster2.57e-15373
anatomical conduit1.52e-14240
temporal lobe5.57e-146
posterior neural tube1.08e-1315
chordal neural plate1.08e-1315
diencephalon1.39e-137
future diencephalon1.39e-137
telencephalic nucleus2.57e-137
gyrus4.42e-126
brainstem2.13e-116
occipital lobe7.51e-115
multi-tissue structure7.74e-11342
limbic system8.79e-115
epithelium1.63e-10306
parietal lobe2.02e-105
cell layer3.00e-10309
organ part1.96e-09218
segmental subdivision of hindbrain4.20e-0912
hindbrain4.20e-0912
presumptive hindbrain4.20e-0912
regional part of diencephalon6.96e-094
corpus striatum7.52e-094
striatum7.52e-094
ventral part of telencephalon7.52e-094
future corpus striatum7.52e-094
gland of diencephalon1.01e-084
neuroendocrine gland1.01e-084
embryo2.80e-08592
segmental subdivision of nervous system2.82e-0813
embryonic structure2.04e-07564
germ layer3.59e-07560
germ layer / neural crest3.59e-07560
embryonic tissue3.59e-07560
presumptive structure3.59e-07560
germ layer / neural crest derived structure3.59e-07560
epiblast (generic)3.59e-07560
organ3.62e-07503
caudate-putamen3.79e-073
dorsal striatum3.79e-073
frontal cortex5.30e-073
developing anatomical structure6.02e-07581
spinal cord6.70e-073
dorsal region element6.70e-073
dorsum6.70e-073


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.