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Coexpression cluster:C1764

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Full id: C1764_occipital_optic_spinal_diencephalon_thalamus_globus_substantia



Phase1 CAGE Peaks

Hg19::chr16:57295953..57295964,-p@chr16:57295953..57295964
-
Hg19::chrX:103041626..103041634,+p@chrX:103041626..103041634
+
Hg19::chrX:103042721..103042782,+p5@PLP1
Hg19::chrX:103046089..103046096,+p@chrX:103046089..103046096
+
Hg19::chrX:103046153..103046162,+p@chrX:103046153..103046162
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube3.73e-10956
neural rod3.73e-10956
future spinal cord3.73e-10956
neural keel3.73e-10956
regional part of nervous system1.70e-9753
regional part of brain1.70e-9753
central nervous system1.21e-8481
brain3.16e-8268
future brain3.16e-8268
regional part of forebrain4.74e-8241
forebrain4.74e-8241
anterior neural tube4.74e-8241
future forebrain4.74e-8241
brain grey matter1.14e-7934
gray matter1.14e-7934
nervous system1.39e-7989
telencephalon2.17e-7934
neural plate1.89e-7682
presumptive neural plate1.89e-7682
neurectoderm1.56e-7286
regional part of telencephalon4.06e-7232
cerebral hemisphere1.26e-7132
adult organism2.21e-65114
ecto-epithelium1.35e-58104
pre-chordal neural plate2.30e-5761
regional part of cerebral cortex3.63e-5322
structure with developmental contribution from neural crest5.61e-47132
cerebral cortex1.58e-4625
pallium1.58e-4625
neocortex8.17e-4620
ectoderm-derived structure8.07e-38171
ectoderm8.07e-38171
presumptive ectoderm8.07e-38171
neural nucleus8.44e-379
nucleus of brain8.44e-379
organ system subdivision4.87e-30223
telencephalic nucleus5.10e-297
basal ganglion6.16e-299
nuclear complex of neuraxis6.16e-299
aggregate regional part of brain6.16e-299
collection of basal ganglia6.16e-299
cerebral subcortex6.16e-299
posterior neural tube1.36e-2615
chordal neural plate1.36e-2615
tube4.29e-26192
brainstem7.78e-256
gyrus6.90e-246
segmental subdivision of nervous system1.19e-1913
anatomical conduit3.82e-19240
corpus striatum1.37e-164
striatum1.37e-164
ventral part of telencephalon1.37e-164
future corpus striatum1.37e-164
segmental subdivision of hindbrain2.89e-1612
hindbrain2.89e-1612
presumptive hindbrain2.89e-1612
anatomical cluster2.39e-14373
epithelium3.49e-14306
spinal cord4.60e-143
dorsal region element4.60e-143
dorsum4.60e-143
organ part4.71e-14218
cell layer5.85e-14309
occipital lobe9.37e-145
medulla oblongata1.66e-133
myelencephalon1.66e-133
future myelencephalon1.66e-133
limbic system1.87e-135
pons4.34e-133
parietal lobe5.61e-135
caudate-putamen6.04e-133
dorsal striatum6.04e-133
frontal cortex8.39e-133
multi-tissue structure1.07e-10342
globus pallidus4.98e-102
pallidum4.98e-102
dorsal plus ventral thalamus6.76e-102
thalamic complex6.76e-102
multi cell component structure8.03e-102
neuron projection bundle8.03e-102
temporal lobe1.41e-096
locus ceruleus1.66e-092
brainstem nucleus1.66e-092
hindbrain nucleus1.66e-092
Ammon's horn1.97e-092
lobe parts of cerebral cortex1.97e-092
hippocampal formation1.97e-092
limbic lobe1.97e-092
caudate nucleus2.14e-092
future caudate nucleus2.14e-092
middle temporal gyrus2.23e-092
middle frontal gyrus3.12e-092
organ3.70e-08503
regional part of metencephalon1.61e-079
metencephalon1.61e-079
future metencephalon1.61e-079
germ layer5.60e-07560
germ layer / neural crest5.60e-07560
embryonic tissue5.60e-07560
presumptive structure5.60e-07560


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.00991994
MA0004.10.626788
MA0006.10.452993
MA0007.10.606704
MA0009.11.11255
MA0014.10.0418333
MA0017.10.496101
MA0019.10.784036
MA0024.11.00439
MA0025.11.24931
MA0027.12.73598
MA0028.10.470679
MA0029.11.02437
MA0030.11.01252
MA0031.10.945567
MA0038.10.736268
MA0040.11.03042
MA0041.10.64667
MA0042.10.612397
MA0043.11.11288
MA0046.11.10134
MA0048.10.195817
MA0050.10.613347
MA0051.10.731787
MA0052.11.03442
MA0055.10.288856
MA0056.10
MA0057.10.189508
MA0058.10.523638
MA0059.10.522232
MA0060.10.321781
MA0061.10.291022
MA0063.10
MA0066.10.736721
MA0067.11.43651
MA0068.10.247962
MA0069.11.09737
MA0070.11.08584
MA0071.11.65981
MA0072.11.0812
MA0073.10.0140295
MA0074.10.730989
MA0076.10.540943
MA0077.11.07324
MA0078.10.836493
MA0081.10.522409
MA0083.11.12028
MA0084.11.62584
MA0087.11.07867
MA0088.10.132006
MA0089.10
MA0090.10.556637
MA0091.10.629594
MA0092.10.588959
MA0093.10.456342
MA0095.10
MA0098.10
MA0100.10.750974
MA0101.10.459973
MA0103.11.12656
MA0105.10.175503
MA0106.10.779931
MA0107.10.378225
MA0108.20.94238
MA0109.10
MA0111.10.5713
MA0113.10.797251
MA0114.10.372523
MA0115.11.35895
MA0116.10.382106
MA0117.11.1512
MA0119.10.504689
MA0122.11.17777
MA0124.11.31673
MA0125.11.23103
MA0130.10
MA0131.10.855546
MA0132.10
MA0133.10
MA0135.11.14377
MA0136.10.743749
MA0139.10.277033
MA0140.10.692258
MA0141.10.520334
MA0142.10.912455
MA0143.10.797437
MA0144.10.356507
MA0145.10.143698
MA0146.10.143081
MA0147.10.386018
MA0148.10.653474
MA0149.10.681935
MA0062.20.284987
MA0035.20.691506
MA0039.20.15493
MA0138.20.837782
MA0002.20.83106
MA0137.20.47779
MA0104.20.320919
MA0047.20.767096
MA0112.20.136971
MA0065.20.880827
MA0150.10.550239
MA0151.10
MA0152.10.69926
MA0153.11.21379
MA0154.10.172764
MA0155.10.130813
MA0156.10.480289
MA0157.10.883854
MA0158.10
MA0159.10.386729
MA0160.10.669748
MA0161.10
MA0162.10.0592265
MA0163.10.168633
MA0164.10.810347
MA0080.20.456437
MA0018.20.781393
MA0099.20.699641
MA0079.20.0442129
MA0102.21.66336
MA0258.10.345771
MA0259.10.395396
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.