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Coexpression cluster:C1816

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Full id: C1816_spinal_Melanocyte_brain_hippocampus_amygdala_corpus_temporal



Phase1 CAGE Peaks

  Short description
Hg19::chr19:30016925..30016951,+ p@chr19:30016925..30016951
+
Hg19::chr1:156611900..156611916,+ p1@BCAN
Hg19::chr1:156611940..156611959,+ p2@BCAN
Hg19::chr1:156611960..156611974,+ p3@BCAN
Hg19::chr1:156621459..156621474,- p@chr1:156621459..156621474
-


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


No GOStat results

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data


Cell Type
Ontology termp-valuen
melanocyte2.79e-1510
melanoblast2.79e-1510
neuronal stem cell8.11e-118
pigment cell2.43e-1014
neuron2.35e-076
neuroblast2.35e-076
electrically signaling cell2.35e-076
Uber Anatomy
Ontology termp-valuen
central nervous system6.04e-8281
neural tube1.25e-8056
neural rod1.25e-8056
future spinal cord1.25e-8056
neural keel1.25e-8056
nervous system3.75e-8089
regional part of nervous system7.32e-7553
regional part of brain7.32e-7553
regional part of forebrain4.81e-6441
forebrain4.81e-6441
anterior neural tube4.81e-6441
future forebrain4.81e-6441
brain4.78e-6368
future brain4.78e-6368
neural plate2.57e-5582
presumptive neural plate2.57e-5582
telencephalon3.62e-5534
brain grey matter6.58e-5534
gray matter6.58e-5534
neurectoderm5.03e-5286
cerebral hemisphere2.06e-5132
regional part of telencephalon2.67e-5132
ecto-epithelium9.54e-46104
adult organism1.79e-45114
pre-chordal neural plate2.39e-4461
ectoderm-derived structure1.34e-41171
ectoderm1.34e-41171
presumptive ectoderm1.34e-41171
regional part of cerebral cortex1.62e-4022
cerebral cortex4.22e-3825
pallium4.22e-3825
neocortex1.74e-3620
structure with developmental contribution from neural crest4.81e-34132
organ system subdivision5.93e-33223
basal ganglion1.08e-189
nuclear complex of neuraxis1.08e-189
aggregate regional part of brain1.08e-189
collection of basal ganglia1.08e-189
cerebral subcortex1.08e-189
neural nucleus3.99e-189
nucleus of brain3.99e-189
posterior neural tube3.94e-1715
chordal neural plate3.94e-1715
tube1.92e-16192
telencephalic nucleus1.18e-147
anatomical cluster2.27e-14373
segmental subdivision of nervous system6.33e-1413
gyrus2.98e-126
segmental subdivision of hindbrain4.40e-1212
hindbrain4.40e-1212
presumptive hindbrain4.40e-1212
brainstem5.60e-126
limbic system1.33e-115
anatomical conduit1.39e-11240
temporal lobe2.54e-116
occipital lobe6.71e-115
parietal lobe1.07e-105
diencephalon4.33e-107
future diencephalon4.33e-107
corpus striatum2.81e-094
striatum2.81e-094
ventral part of telencephalon2.81e-094
future corpus striatum2.81e-094
organ part4.35e-09218
regional part of diencephalon1.35e-084
multi-tissue structure6.53e-08342
embryo8.78e-08592
epithelium1.12e-07306
regional part of metencephalon1.71e-079
metencephalon1.71e-079
future metencephalon1.71e-079
cell layer1.79e-07309
caudate-putamen2.23e-073
dorsal striatum2.23e-073
spinal cord4.23e-073
dorsal region element4.23e-073
dorsum4.23e-073
pons7.61e-073
medulla oblongata8.93e-073
myelencephalon8.93e-073
future myelencephalon8.93e-073


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.11.40197
MA0004.10.626788
MA0006.10.452993
MA0007.10.606704
MA0009.11.11255
MA0014.13.07977
MA0017.10.496101
MA0019.10.784036
MA0024.11.00439
MA0025.11.24931
MA0027.12.73598
MA0028.10.470679
MA0029.11.02437
MA0030.11.01252
MA0031.10.945567
MA0038.10.736268
MA0040.11.03042
MA0041.10.64667
MA0042.10.612397
MA0043.11.11288
MA0046.11.10134
MA0048.11.7027
MA0050.10.613347
MA0051.10.731787
MA0052.11.03442
MA0055.13.37159
MA0056.10
MA0057.12.36624
MA0058.10.523638
MA0059.10.522232
MA0060.10.321781
MA0061.10.291022
MA0063.10
MA0066.10.736721
MA0067.11.43651
MA0068.11.98392
MA0069.11.09737
MA0070.11.08584
MA0071.10.695094
MA0072.11.0812
MA0073.11.05325
MA0074.10.730989
MA0076.10.540943
MA0077.11.07324
MA0078.10.836493
MA0081.10.522409
MA0083.11.12028
MA0084.11.62584
MA0087.11.07867
MA0088.10.818263
MA0089.10
MA0090.10.556637
MA0091.10.629594
MA0092.10.588959
MA0093.10.456342
MA0095.10
MA0098.10
MA0100.10.750974
MA0101.10.459973
MA0103.10.442769
MA0105.12.26263
MA0106.10.779931
MA0107.10.378225
MA0108.20.94238
MA0109.10
MA0111.10.5713
MA0113.10.797251
MA0114.10.372523
MA0115.11.35895
MA0116.10.382106
MA0117.11.1512
MA0119.11.25946
MA0122.11.17777
MA0124.11.31673
MA0125.11.23103
MA0130.10
MA0131.10.855546
MA0132.10
MA0133.10
MA0135.11.14377
MA0136.10.743749
MA0139.11.39016
MA0140.10.692258
MA0141.10.520334
MA0142.10.912455
MA0143.10.797437
MA0144.10.356507
MA0145.10.143698
MA0146.10.333008
MA0147.10.386018
MA0148.10.653474
MA0149.10.681935
MA0062.20.284987
MA0035.20.691506
MA0039.25.85821
MA0138.20.837782
MA0002.20.30855
MA0137.20.47779
MA0104.20.320919
MA0047.20.767096
MA0112.20.425004
MA0065.20.449243
MA0150.10.550239
MA0151.10
MA0152.10.69926
MA0153.11.21379
MA0154.11.57192
MA0155.11.3196
MA0156.10.480289
MA0157.10.883854
MA0158.10
MA0159.11.00463
MA0160.10.669748
MA0161.10
MA0162.12.27598
MA0163.11.05321
MA0164.10.810347
MA0080.20.456437
MA0018.20.781393
MA0099.20.699641
MA0079.215.017
MA0102.21.66336
MA0258.10.345771
MA0259.10.395396
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
ZNF263#1012746.577473309608540.0009875103237900160.00709267524285163



Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.