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Coexpression cluster:C1008

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Full id: C1008_globus_thalamus_optic_medulla_parietal_caudate_hippocampus



Phase1 CAGE Peaks

  Short description
Hg19::chr11:98185887..98185890,+ p@chr11:98185887..98185890
+
Hg19::chr13:78281161..78281170,+ p@chr13:78281161..78281170
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Hg19::chr1:231945981..231945983,+ p@chr1:231945981..231945983
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Hg19::chr20:40282556..40282558,+ p@chr20:40282556..40282558
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Hg19::chr2:86150436..86150440,+ p@chr2:86150436..86150440
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Hg19::chr3:181459063..181459078,+ p@chr3:181459063..181459078
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Hg19::chr3:47054521..47054522,+ p@chr3:47054521..47054522
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Hg19::chr7:91092835..91092842,+ p@chr7:91092835..91092842
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Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


No GOStat results

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset


uberon_data


Uber Anatomy
Ontology termp-valuen
neural tube4.31e-7756
neural rod4.31e-7756
future spinal cord4.31e-7756
neural keel4.31e-7756
regional part of nervous system7.86e-7553
regional part of brain7.86e-7553
regional part of forebrain6.22e-6041
forebrain6.22e-6041
anterior neural tube6.22e-6041
future forebrain6.22e-6041
brain grey matter7.78e-5834
gray matter7.78e-5834
brain7.50e-5768
future brain7.50e-5768
neural plate2.36e-5682
presumptive neural plate2.36e-5682
regional part of telencephalon3.38e-5432
neurectoderm1.40e-5386
central nervous system1.00e-5181
telencephalon6.17e-5134
nervous system1.87e-5089
cerebral hemisphere1.77e-4732
pre-chordal neural plate3.89e-4461
ecto-epithelium1.03e-43104
adult organism5.74e-40114
neural nucleus1.40e-399
nucleus of brain1.40e-399
basal ganglion2.10e-399
nuclear complex of neuraxis2.10e-399
aggregate regional part of brain2.10e-399
collection of basal ganglia2.10e-399
cerebral subcortex2.10e-399
telencephalic nucleus1.87e-377
structure with developmental contribution from neural crest1.52e-36132
regional part of cerebral cortex1.52e-3022
neocortex4.08e-2720
cerebral cortex7.73e-2725
pallium7.73e-2725
ectoderm-derived structure9.29e-25171
ectoderm9.29e-25171
presumptive ectoderm9.29e-25171
caudate-putamen1.38e-223
dorsal striatum1.38e-223
segmental subdivision of nervous system2.23e-2013
tube6.31e-20192
gyrus7.49e-206
organ system subdivision1.08e-19223
posterior neural tube1.50e-1715
chordal neural plate1.50e-1715
corpus striatum4.24e-174
striatum4.24e-174
ventral part of telencephalon4.24e-174
future corpus striatum4.24e-174
dorsal plus ventral thalamus4.31e-162
thalamic complex4.31e-162
globus pallidus5.83e-162
pallidum5.83e-162
caudate nucleus7.31e-162
future caudate nucleus7.31e-162
middle temporal gyrus8.50e-162
middle frontal gyrus1.23e-152
segmental subdivision of hindbrain1.88e-1512
hindbrain1.88e-1512
presumptive hindbrain1.88e-1512
anatomical conduit4.07e-15240
regional part of metencephalon2.14e-139
metencephalon2.14e-139
future metencephalon2.14e-139
organ part1.73e-12218
epithelium3.50e-12306
cell layer5.07e-12309
brainstem7.63e-126
pons8.47e-113
frontal cortex9.82e-113
multi-tissue structure2.34e-10342
diencephalon3.60e-107
future diencephalon3.60e-107
temporal lobe3.96e-106
anatomical cluster4.01e-10373
cranial nerve II3.58e-091
cranial nerve3.58e-091
nerve trunk3.58e-091
nerve connecting eye with brain3.58e-091
nerve3.58e-091
retinal neural layer3.58e-091
presumptive neural retina3.58e-091
substantia nigra9.02e-091
midbrain nucleus9.02e-091
regional part of midbrain9.02e-091
midbrain9.02e-091
presumptive midbrain9.02e-091
midbrain neural tube9.02e-091
olfactory region1.65e-081
primary subdivision of skull1.65e-081
cranium1.65e-081
neurocranium1.65e-081
chondrocranium1.65e-081
cartilaginous neurocranium1.65e-081
head paraxial mesoderm1.65e-081
regional part of diencephalon1.72e-084


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.0264723
MA0004.10.455723
MA0006.10.300178
MA0007.10.437331
MA0009.10.918715
MA0014.10.00962431
MA0017.10.337901
MA0019.10.602411
MA0024.10.813542
MA0025.11.05265
MA0027.12.5321
MA0028.10.315574
MA0029.10.832916
MA0030.10.821423
MA0031.10.756713
MA0038.10.557409
MA0040.10.838784
MA0041.12.07464
MA0042.11.12605
MA0043.10.919032
MA0046.10.90778
MA0048.10.0955945
MA0050.10.443405
MA0051.10.553205
MA0052.10.842664
MA0055.10.524515
MA0056.10
MA0057.10.0912556
MA0058.10.362328
MA0059.10.361075
MA0060.10.190336
MA0061.10.165998
MA0063.10
MA0066.10.557833
MA0067.11.23721
MA0068.10.415214
MA0069.10.903908
MA0070.10.892666
MA0071.10.518907
MA0072.10.888148
MA0073.10.0136601
MA0074.10.552456
MA0076.10.377799
MA0077.10.880402
MA0078.10.652193
MA0081.10.361233
MA0083.10.926258
MA0084.11.42483
MA0087.10.885691
MA0088.10.054222
MA0089.10
MA0090.10.391903
MA0091.10.458301
MA0092.10.421159
MA0093.10.818737
MA0095.10
MA0098.10
MA0100.10.571227
MA0101.10.30624
MA0103.10.291333
MA0105.10.0818021
MA0106.10.59853
MA0107.10.236528
MA0108.20.753643
MA0109.10
MA0111.10.405141
MA0113.10.614917
MA0114.10.231781
MA0115.11.1606
MA0116.10.239768
MA0117.10.956472
MA0119.10.913661
MA0122.10.982472
MA0124.11.11898
MA0125.11.0347
MA0130.10
MA0131.10.670358
MA0132.10
MA0133.10
MA0135.10.949204
MA0136.10.564434
MA0139.10.155155
MA0140.10.516266
MA0141.10.944441
MA0142.10.724856
MA0143.10.615094
MA0144.10.623945
MA0145.10.220937
MA0146.10.0399277
MA0147.10.243042
MA0148.10.480298
MA0149.10.506665
MA0062.20.161302
MA0035.20.515566
MA0039.20.00133745
MA0138.20.653421
MA0002.20.179788
MA0137.20.321796
MA0104.20.189646
MA0047.20.586412
MA0112.20.0572179
MA0065.20.226158
MA0150.10.386144
MA0151.10
MA0152.10.52279
MA0153.11.01778
MA0154.10.0799828
MA0155.10.0535085
MA0156.10.865715
MA0157.10.697424
MA0158.10
MA0159.10.243637
MA0160.10.495355
MA0161.10
MA0162.10.0163939
MA0163.10.0517199
MA0164.10.627336
MA0080.20.303167
MA0018.20.599912
MA0099.20.523145
MA0079.21.80475e-05
MA0102.21.46209
MA0258.10.603127
MA0259.10.25092
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


No analysis results for this cluster

Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.