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Coexpression cluster:C2352

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Full id: C2352_medial_thalamus_parietal_spinal_occipital_globus_olfactory



Phase1 CAGE Peaks

Hg19::chr15:84230572..84230583,+p@chr15:84230572..84230583
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Hg19::chr5:58149735..58149744,+p@chr5:58149735..58149744
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Hg19::chr7:30197516..30197529,+p@chr7:30197516..30197529
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Hg19::chrX:122622679..122622689,+p@chrX:122622679..122622689
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube1.09e-10556
neural rod1.09e-10556
future spinal cord1.09e-10556
neural keel1.09e-10556
regional part of nervous system2.21e-9453
regional part of brain2.21e-9453
central nervous system1.10e-9081
nervous system5.83e-8189
brain1.64e-7968
future brain1.64e-7968
regional part of forebrain7.83e-7441
forebrain7.83e-7441
anterior neural tube7.83e-7441
future forebrain7.83e-7441
neural plate5.89e-7082
presumptive neural plate5.89e-7082
neurectoderm2.36e-6686
brain grey matter2.94e-6034
gray matter2.94e-6034
telencephalon6.45e-6034
adult organism2.48e-54114
ecto-epithelium1.57e-53104
cerebral hemisphere2.75e-5332
regional part of telencephalon3.15e-5332
pre-chordal neural plate8.05e-4861
structure with developmental contribution from neural crest5.21e-43132
regional part of cerebral cortex1.41e-3922
ectoderm-derived structure1.21e-38171
ectoderm1.21e-38171
presumptive ectoderm1.21e-38171
cerebral cortex1.36e-3425
pallium1.36e-3425
neocortex1.46e-3220
posterior neural tube2.42e-3115
chordal neural plate2.42e-3115
neural nucleus2.80e-299
nucleus of brain2.80e-299
organ system subdivision3.21e-29223
gyrus7.34e-266
tube3.04e-25192
brainstem4.75e-246
basal ganglion1.17e-229
nuclear complex of neuraxis1.17e-229
aggregate regional part of brain1.17e-229
collection of basal ganglia1.17e-229
cerebral subcortex1.17e-229
telencephalic nucleus1.36e-217
segmental subdivision of hindbrain1.22e-2012
hindbrain1.22e-2012
presumptive hindbrain1.22e-2012
segmental subdivision of nervous system5.89e-1913
anatomical conduit1.64e-18240
diencephalon6.26e-157
future diencephalon6.26e-157
limbic system3.12e-145
frontal cortex4.88e-143
anatomical cluster5.98e-14373
parietal lobe8.58e-145
spinal cord1.06e-133
dorsal region element1.06e-133
dorsum1.06e-133
epithelium1.18e-13306
cell layer1.94e-13309
pons3.96e-133
medulla oblongata1.12e-123
myelencephalon1.12e-123
future myelencephalon1.12e-123
organ part1.62e-11218
regional part of metencephalon2.28e-119
metencephalon2.28e-119
future metencephalon2.28e-119
regional part of diencephalon1.91e-104
corpus striatum2.47e-104
striatum2.47e-104
ventral part of telencephalon2.47e-104
future corpus striatum2.47e-104
middle temporal gyrus2.86e-102
middle frontal gyrus4.27e-102
dorsal plus ventral thalamus4.87e-102
thalamic complex4.87e-102
Ammon's horn8.25e-102
lobe parts of cerebral cortex8.25e-102
hippocampal formation8.25e-102
limbic lobe8.25e-102
globus pallidus1.02e-092
pallidum1.02e-092
locus ceruleus1.51e-092
brainstem nucleus1.51e-092
hindbrain nucleus1.51e-092
multi-tissue structure8.48e-09342
germ layer1.76e-07560
germ layer / neural crest1.76e-07560
embryonic tissue1.76e-07560
presumptive structure1.76e-07560
germ layer / neural crest derived structure1.76e-07560
epiblast (generic)1.76e-07560
embryonic structure2.32e-07564
developing anatomical structure7.28e-07581
caudate-putamen8.69e-073
dorsal striatum8.69e-073


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.0214529
MA0004.10.71247
MA0006.10.532262
MA0007.10.6918
MA0009.11.20602
MA0014.10.0695829
MA0017.10.577281
MA0019.12.02743
MA0024.11.09684
MA0025.11.34373
MA0027.12.83281
MA0028.10.550763
MA0029.11.11704
MA0030.11.10506
MA0031.11.03735
MA0038.10.824639
MA0040.11.12314
MA0041.11.73823
MA0042.10.697662
MA0043.11.20635
MA0046.11.19471
MA0048.10.25531
MA0050.10.69864
MA0051.10.820063
MA0052.11.12718
MA0055.10.125954
MA0056.10
MA0057.10.248209
MA0058.10.605914
MA0059.10.604454
MA0060.10.393285
MA0061.10.360128
MA0063.10
MA0066.10.825101
MA0067.11.53181
MA0068.10.313194
MA0069.11.19071
MA0070.11.17908
MA0071.10.782546
MA0072.11.1744
MA0073.10.00636811
MA0074.10.819248
MA0076.10.623864
MA0077.11.16637
MA0078.10.926725
MA0081.10.604638
MA0083.11.21381
MA0084.11.72172
MA0087.11.17185
MA0088.10.182167
MA0089.10
MA0090.10.640115
MA0091.10.715356
MA0092.10.673508
MA0093.10.535768
MA0095.10
MA0098.10
MA0100.10.83965
MA0101.10.539569
MA0103.10.521546
MA0105.10.232357
MA0106.10.869173
MA0107.10.453492
MA0108.21.03412
MA0109.10
MA0111.10.655276
MA0113.10.886811
MA0114.10.447443
MA0115.11.45393
MA0116.10.457606
MA0117.11.24497
MA0119.12.44319
MA0122.11.27173
MA0124.11.41151
MA0125.11.32534
MA0130.10
MA0131.10.94608
MA0132.10
MA0133.10
MA0135.11.23748
MA0136.10.832277
MA0139.10.344952
MA0140.10.779643
MA0141.10.602484
MA0142.11.00381
MA0143.10.887001
MA0144.10.430413
MA0145.10.195821
MA0146.10.061409
MA0147.10.46175
MA0148.10.739888
MA0149.10.769072
MA0062.20.353589
MA0035.20.778873
MA0039.20.0247757
MA0138.20.928035
MA0002.20.98779
MA0137.20.558189
MA0104.20.392359
MA0047.20.856092
MA0112.20.187982
MA0065.20.199162
MA0150.10.633493
MA0151.10
MA0152.10.78681
MA0153.11.30799
MA0154.10.229241
MA0155.10.180766
MA0156.10.560797
MA0157.10.97481
MA0158.10
MA0159.10.462502
MA0160.10.756582
MA0161.10
MA0162.10.0928415
MA0163.10.253219
MA0164.10.90014
MA0080.20.535868
MA0018.20.870662
MA0099.20.7872
MA0079.20.000248021
MA0102.21.75932
MA0258.10.418966
MA0259.10.471671
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.