Property:Def
From FANTOM5_SSTAR
The type of this property is text
0
"Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." [CARO:mah] +
"A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." [CARO:mah] +
"An occurrent [span:Occurrent] that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity." [span:ProcessualEntity] +
"A cell culture cell that is part of a cell culture that does not have the capacity to proliferate indefinitely." [ReO:mhb] +
"Root Term for the FANTOM5 sample ontology. Should only be viewed by FANTOM5 consortium members until one year after data freeze (~June 2012)." [GOC:tfm] +
"A cell culture cell that is part of a cell line having the capacity to proliferate indefinitely if given appropriate space and nutrients." [ReO:mhb] +
"Lower, narrow portion of the uterus where it joins with the top end of the vagina." [Wikipedia:Cervix] +
"A sample consisting of in vivo cell material.\nNOTE: The distinction between a primary cell line sample and in vivo cell sample may be difficult." [GOC:tfm] +
"A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment)." [CARO:mah] +
"a protuberance in vertebrates that houses the nostrils, or nares, which admit and expel air for respiration in conjunction with the mouth. Behind the nose are the olfactory mucosa and the sinuses. Behind the nasal cavity, air next passes through the pharynx, shared with the digestive system, and then into the rest of the respiratory system. In humans, the nose is located centrally on the face; on most other mammals, it is on the upper tip of the snout[WP]. GO: The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity)." [Wikipedia:Nose] +
"Regions of the pancreas that contain its endocrine (i.e., hormone-producing) cells." [Wikipedia:Islets_of_Langerhans] +
"The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands [GO]. An endocrine gland located ventral to the diencephalon and derived from mixed neuroectodermal and non neuroectodermal origin [ZFIN]." [Wikipedia:Pituitary_gland, ZFIN:curator] +
"Nervous structures including ganglia outside of the central nervous system. Divided into somatic nervous system and autonomic nervous system" [FB:gg, OMD:peripheral+nervous+system, Wikipedia:Peripheral_nervous_system, ZFIN:curator] +
"The parasympathetic nervous system (PSNS) is a division of the autonomic nervous system (ANS), along with the sympathetic nervous system (SNS) and enteric nervous system (ENS). The ANS is a subdivision of the peripheral nervous system (PNS). ANS sends fibers to three tissues: cardiac muscle, smooth muscle, or glandular tissue. This stimulation, sympathetic or parasympathetic, is to control smooth muscle contraction, regulate cardiac muscle, or stimulate or inhibit glandular secretion [Wikipedia]. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia [GO]." [Wikipedia:Parasympathetic_nervous_system] +
"The part of the peripheral nervous system consisting of efferent nerves responsible for stimulating muscle contraction, including all the neurons connected with skeletal muscles, skin, and sense organs[WP, modified]." [Wikipedia:Somatic_nervous_system] +
"The Sympathetic Nervous System (SNS) is a branch of the autonomic nervous system along with the enteric nervous system and parasympathetic nervous system. It is always active at a basal level (called sympathetic tone) and becomes more active during times of stress. Its actions during the stress response comprise the fight-or-flight response [Wikipedia]. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter [GO]." [Wikipedia:Sympathetic_nervous_system] +
"A sub-region of the skin. Note the distinct between the entire skin of the body, of which there is only 1 in an organism, and zones of skin, of which there can be many. Examples: skin of knee" [GOC:cjm, Wikipedia:Skin] +
"Structural anatomical relation which holds between each anatomical entity of one to three dimensions and some immaterial anatomical entity of one lower dimension such that the latter demarcates (delimits) the former from its neighborhood." [FMA:256502] +
"The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin[GO]." [GOC:GO, Wikipedia:Islets_of_Langerhans] +
"The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field[GO]. The eye contains the following parts (when they are present in the organism): the eyeball (eye proper), the lacrimal apparatus, the conjuctival, the eyelid // " [GO:0043010, UBERON:cjm] +
"Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts. with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system" [GO:0035295, PMID:12526790] +
"Major subdivision of an organism that protrudes from the body[DOS]. Organ or organ part that is attached to the body of an organism. For example a limb[GO, modified]. An appendage is an external body part, or natural prolongation, that protrudes from an organism's body, such as a vertebrate's limbs[BILA]." [BILA:0000018, GO:0048736, Wikipedia:Appendage] +
"A CD34-positive hematopoietic stem cell provided by CET (Thermoscientific HMpC-500)." [GOC:tfm] +
"Oval or bean shaped bodies (1 - 30 mm in diameter) located along the lymphatic system. Lymph nodes are garrisons of B, T, and other immune cells. Lymph nodes are found all through the body, and act as filters or traps for foreign particles. They contain white blood cells that use oxygen to process. Thus they are important in the proper functioning of the immune system. The lymph node is surrounded by a fibrous capsule, and inside the lymph node the fibrous capsule extends to form trabeculae. The substance of the lymph node is divided into the outer cortex and the inner medulla surrounded by the former all around except for at the hilum, where the medulla comes in direct contact with the surface. Thin reticular fibers, elastin and reticular fibers form a supporting meshwork called reticular network (RN) inside the node, within which the white blood cells (WBCs), most prominently, lymphocytes are tightly packed as follicles in the cortex. Elsewhere, there are only occasional WBCs. The RN provides not just the structural support, but also provide surface for adhesion of the dendritic cells, macrophages and lymphocytes. It allows for exchange of material with blood through the high endothelial venules and provides the growth and regulatory factors necessary for activation and maturation of immune cells[WP]." [GAID:947, Wikipedia:Lymph_node] +
"A CD34-positive hematopoietic stem cell provided by 3HBiomedical (3H100-60-5)." [GOC:tfm] +
"A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:tfm, MESH:A.11.872] +
"A stem cell that self-renews as well as give rise to a single mature cell type." [GOC:tfm] +
"A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119." [GOC:add, GOC:DSD, GOC:tfm, PMID:19022770] +
"A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative)." [GOC:add, ISBN:0721601464] +
"A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring." [GOC:tfm, ISBN:0721662544] +
"A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus." [GOC:add, http://www.clt.astate.edu/wwilliam/, http://www.copewithcytokines.de, PMID:1104740] +
"a smooth membrane consisting of a thin layer of cells which excrete serous fluid. Serous membranes line and enclose several body cavities, known as serous cavities, where they secrete a lubricating fluid which reduces friction from muscle movement. Serosa is not to be confused with adventitia, a connective tissue layer which binds together structures rather than reducing friction between them. Each serous membrane is composed of a secretory epithelial layer and a connective tissue layer underneath. The epithelial layer, known as mesothelium, consists of a single layer of avascular flat nucleated cells (cuboidal epithelium) which produce the lubricating serous fluid. This fluid has a consistency similar to thin mucus. These cells are bound tightly to the underlying connective tissue. The connective tissue layer provides the blood vessels and nerves for the overlying secretory cells, and also serves as the binding layer which allows the whole serous membrane to adhere to organs and other structures.[WP]." [Wikipedia:Serosa, Wikipedia:Serous_membrane] +
"Dense regular connective tissue that connects muscle to bone[VSAO]." [VSAO:0000073, Wikipedia:Tendon] +
"A biological tissue mass, most commonly a mass of nerve cell bodies." [Wikipedia:Ganglion] +
"Neural stem cell is characterized as an undifferentiated cell that originates from the neuroectoderm and has the capacity both to perpetually self-renew without differentiating and to generate multiple types of lineage-restricted progenitors." [GOC:tfm, http://en.wikipedia.org/wiki/Neural_stem_cell, MESH:D058953, PMID:15247488] +
"An eye with one concave chamber. Note that 'simple' does not imply a reduced level of complexity or acuity." [Wikipedia:Eye#Simple_eyes] +
"A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. These cells are CD34-positive, and express Gata-1, Gata2, C/EBPa, and Pu.1." [GOC:add, GOC:dsd, GOC:tfm, ISBN:0878932437, MESH:D023461, PMCID:PMC2212039, PMID:10724173, PMID:16551251] +
"A progenitor cell committed to the megakaryocyte and erythroid lineages." [GOC:add, GOC:tfm] +
"A oligopotent progenitor cell committed to the lymphoid lineage." [GOC:add, GOC:dsd, GOC:tfm, PMID:10407577, PMID:16551251] +
"A tubular structure that contains, conveys body fluid, such as blood or lymph." [UBERON:cjm] +
"A precursor cell of the myogenic lineage that develops from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes." [GOC:tfm, MESH:A.11.635] +
"Muscular duct that propels urine from the kidneys to the urinary bladder, or related organs. In humans, organ with organ cavity which connects the renal sinus to the urinary bladder. Examples: the right and the left ureters." [FMA:9704, GO:0090189, Wikipedia:Ureter] +
"A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped." [http://63.198.234.228/OpenFMA/Fibroblast.html, ISBN:0517223651, MESH:A.11.329.228] +
"A tube which connects the urinary bladder to the outside of the body. In males, the urethra travels through the penis, and carries semen as well as urine. In females, the urethra is shorter and emerges above the vaginal opening. The external urethral sphincter is a striated muscle that allows voluntary control over urination." [Wikipedia:Urethra] +
"An immature cartilage-producing cell found in growing cartilage." [GOC:tfm, ISBN:0618947256] +
"A tube shaped portion of tissue lined with epithelial cells that collects secretions and routes them to their destination[ZFA]." [Wikipedia:Duct_(anatomy), ZFA:0005171] +
"The large intestine consists of the cecum and colon[WP]. Organ with organ cavity which is continuous proximally with the small intestine and distally with the anal canal.[FMA]." [FMA:7201, Wikipedia:Large_intestine_(anatomy)] +
"Material anatomical entity that has inherent 3D shape and is generated by coordinated expression of the organism's own genome." [CARO:0000003] +
"A bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone." [MESH:A.11.329.629] +
"Anatomical structure that performs a specific function or group of functions [WP]. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions[GO]." [Wikipedia:Organ_(anatomy)] +
"Organ region with one or more fixed or anchored fiat boundaries. Examples: artery, trunk of nerve, cervical part of esophagus, pelvic part of vagina, horn of thyroid cartilage, anterior segment of eyeball[FMA]." [FMA:86140] +
"anatomical structure which has as its direct parts two or more types of tissue and is continuous with one or more anatomical structures likewise constituted by two or more portions of tissues distinct from those of their complement. Examples: osteon, cortical bone, neck of femur, bronchopulmonary segment, left lobe of liver, anterior right side of heart, interventricular branch of left coronary artery, right atrium, mitral valve, head of pancreas[FMA]." [FMA:82472] +
"anatomical structure that is part of the respiratory system. In mammals consists of upper and lower tracts" [UBERON:cjm] +
"A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina." [FB:ma, GOC:tfm, MESH:A.11.436] +
"The stage of development at which the animal is fully formed, including immaturity and maturity. Includes both juvenile stage, and adult stage. " [UBERON:cjm] +
"A capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney[GO]." [MP:0005325, Wikipedia:Glomerulus] +
"Anatomical cluster consisting of the skeletal elements and articular elements that are part of an individual subdivision of the organism." [UBERON:cjm, UBERONREF:0000003] +
"The surface ectoderm (or external ectoderm forms the following structures: Skin Epithelium of the mouth and nasal cavity saliavary glands, and glands of mouth and nasal cavity Enamel - as a side note dentin and dental pulp are formed from ectomesenchyme which is derived from ectoderm Epithelium of pineal and pituitary glands Lens and cornea of the eye Apical ectodermal ridge inducing development of the limb buds of the embryo. Sensory receptors in epidermis [WP,unvetted]." [Wikipedia:External_ectoderm] +
"A flattened epithelial cell of mesenchymal origin that lines the serous cavity." [GOC:tfm, ISBN:0721662544] +
"An anatomical structure that develops from the ectoderm, mesoderm and endoderm." [UBERON:cjm] +
"the organs associated with producing offspring in the gender that produces spermatozoa." [MP:0001145] +
"A cell which moves among different tissues of the body, via blood, lymph, or other medium." [GOC:add] +
"In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney[GO]. One of three excretory organs that develop in vertebrates. It serves as the main excretory organ of aquatic vertebrates and as a temporary kidney in higher vertebrates. composed of the mesonephric duct (also called the Wolffian duct), mesonephric tubules, and associated capillary tufts. A single tubule and its associated capillary tuft is called a mesonephric excretory unit; these units are similar in structure and function to nephrons of the adult kidney. The mesonephros is derived from intermediate mesoderm in the vertebrate embryo." [GO:0001823, Wikipedia:Mesonephros] +
"A mesonephric tubule is an epithelial tube that is part of the mesonephros[GO]. Genital ridge that is next to the mesonephros[WP]." [Wikipedia:Mesonephric_tubules] +
"A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." [GOC:add, GOC:tfm, ISBN:0781735149] +
"a protrusion from the mesonephric duct during the development of the urinary and reproductive organs. It later develops into the adult kidney, except for the nephrons, which, in contrast, originate from the metanephric blastema[WP]. epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme[MP]" [MP:0010979, PMID:19828308, Wikipedia:Ureteric_bud] +
"Mass of cells inside the primordial embryo that will eventually give rise to the definitive structures of the fetus. This structure forms in the earliest steps of development, before implantation into the endometrium of the uterus has occurred. The ICM lies within the blastocoele (more correctly termed 'blastocyst cavity', as it is not strictly homologous to the blastocoele of anamniote vertebrates) and is entirely surrounded by the single layer of cells called trophoblast." [Wikipedia:Inner_cell_mass] +
"Aggregate of cells forming the outer layer of a blastocyst, which provide nutrients to the embryo and develop into a large part of the placenta. They are formed during the first stage of pregnancy and are the first cells to differentiate from the fertilized egg." [Wikipedia:Trophoblast] +
"the epiblast and the hypoblast, evolved from the embryoblast" [Wikipedia:Bilaminar_disc] +
"A specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. This cell has the following markers: tartrate-resistant acid phosphatase type 5-positive, PU.1-positive, c-fos-positive, nuclear factor NF-kappa-B p100 subunit-positive, tumor necrosis factor receptor superfamily member 11A-positive and macrophage colony-stimulating factor 1 receptor-positive." [GO_REF:0000031, GOC:add, GOC:tfm, ISBN:0781735149, PMID:10428500, PMID:15055519, PMID:17380158] +
"A leukocyte with abundant granules in the cytoplasm." [GOC:amm, GOC:tfm, MESH:A.11.118.637.415] +
"Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA]" [FMA:7145] +
"A cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. Progenitors leave bone marrow and mature in connective and mucosal tissue. Mature mast cells are found in all tissues, except the bloodstream. Their phenotype is CD117-high, CD123-negative, CD193-positive, CD200R3-positive, and FceRI-high. Stem-cell factor (KIT-ligand; SCF) is the main controlling signal of their survival and development." [GOC:add, GOC:dsd, GOC:tfm, ISBN:068340007X, MESH:A.11.329.427, MESH:D008407, PMCID:PMC1312421, PMCID:PMC2855166, PMID:15153310, PMID:16455980, PMID:19671378, PMID:212366338, PMID:9354811] +
"A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells." [GOC:tfm, ISBN:0517223651, ISBN:0721662544] +
"A sample identified by whether its a tissue, a cell-line, or a cell type isolated in vivo." [] +
"An entire span of an organism's life, commencing with the zygote stage and ending in the death of the organism." [UBERON:cjm] +
"A spatiotemporal region encompassing some part of the life cycle of an organism." [UBERON:cjm] +
"A cell type derived from culturing early stage mouse embryos. Not clear if this cell type exists in vivo, so for now will reference higher level fibroblasts." [GOC:tfm] +
"An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm." [GOC:tfm, http://63.198.234.228/OpenFMA/Endothelial%20cell.html, https://sourceforge.net/tracker/?func +
"A mesenchymal stem cell of umibilical cord blood provided by CET(Thermoscientific HMpC-500)." [GOC:tfm] +
"Portion of tissue, that consists of one or more layers of cells connected to each other by cell junctions" [UBERON:cjm] +
"A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses." [CARO:0001001, FBbt:00005099, FBC:DOS] +
"A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons." [MESH:A.08.637] +
"Anatomical structure consisting of a discrete aggregate of neuronal soma[GO]." [GO:0048857, GO_REF:0000021, Wikipedia:Nucleus_(neuroanatomy)] +
"A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together." [GOC:tfm, ISBN:0721662544] +
"A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury." [GOC:dsd, GOC:tfm, MESH:A.08.637.200, MESH:D001253, PMID:11746784, PMID:12162730, PMID:12898703, PMID:20942978] +
"A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system." [MESH:A.08.637.600] +
"A central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive." [GOC:add, GOC:dsd, GOC:tfm, ISBN:0721601464, MESH:D017628, PMID:11517395, PMID:12430718, PMID:14561199, PMID:14612429, PMID:16177057, PMID:19461673, PMID:2089275] +
"A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. This cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs." [FB:ma, GOC:dsd, http://en.wikipedia.org/wiki/Mesenchymal_stem_cell, http://www.copewithcytokines.de/cope.cgi?key +
"An inactive fibroblast; cytoplasm is sparse, endoplasmic reticulum is scanty with flattened nucleus. Term used by some histologists; when fibroblasts become relatively inactive in fiber formation. However, this cell has the potential for fibrogenesis in quiescent connective tissue of the adult, as well as during development, other histologists prefer to use the term fibroblast in all circumstances. These cells represent ~0.5% of peripheral blood leukocytes." [GOC:dsd, GOC:tfm, ISBN:0412046911, ISBN:0517223651, PMID:11641248, PMID:15010326, PMID:17607298, PMID:18222966, PMID:8790603, PMID:9551999] +
"A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides." [MESH:A.11.329.114] +
"A mature osteoblast that has become embedded in the bone matrix. They occupy a small cavity, called lacuna, in the matrix and are connected to adjacent osteocytes via protoplasmic projections called canaliculi." [GOC:tfm, MESH:A.11.329.629.500] +
"A pigment cell derived from the neural crest. Contains melanin-filled pigment granules, which gives a brown to black appearance." [SANBI:mhl] +
"A specialized epithelial cell that is capable of synthesizing and secreting certain biomolecules." [GOC:tfm] +
"A cell that specializes in controlled release of one or more substances." [GOC:tfm, ISBN:0721662544] +
"Segment of the alimentary canal extending from the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine." [GOC:GO, Wikipedia:Intestine] +
"Anatomical conduit that connects two adjacent body spaces, surrounded by two or more subdivisions of two or more organs. Examples: right atrioventricular orifice, orifice of artery, hilum of kidney, porta hepatis[FMA,modified]." [FMA:3724] +
"Posterior opening that serves as the only such opening for the intestinal and urinary tracts of certain animal species" [Wikipedia:Cloaca] +
"A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions." [MESH:A.06.407] +
"Structure in the development of the urinary and reproductive organs[WP]. endoderm-lined chamber into which the hidgut and allantois empty in early embryos[MP]." [MP:0010115, Wikipedia:Cloaca_(embryology)] +
"An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas." [GOC:tfm, SANBI:mhl] +
"Part of the human body only present in the development of the urinary and reproductive organs. It is the ventral part of the cloaca, formed after the cloaca separates from the rectum. It eventually becomes, among other things, the bladder[WP]. ventral part of the cloaca remaining after septation of the rectum, which further develops into part of the bladder, part of the prostatic part of the male urethra and the urethra and vestibule in females[MP]." [Wikipedia:Definitive_urogenital_sinus] +
"An endocrine cell that has the specialized function to produce and secrete hormones in response to neuronal signals." [MESH:A.06.688] +
"First portion of the digestive tract[WP]. The portion of the digestive that develops from the stomodeum" [Wikipedia:Mouth] +
"A cell that stores epinephrine secretory vesicles. During times of stress, the nervous system signals the vesicles to secrete their hormonal content. Their name derives from their ability to stain a brownish color with chromic salts. Characteristically, they are located in the adrenal medulla and paraganglia of the sympathetic nervous system." [MESH:A.06.224.161] +
"A cell that secretes insulin and is located towards the center of the islets of Langerhans." [GOC:tfm, ISBN:0517223651] +
"Organ that functions in gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms." [GO:0007585] +
"A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin." [FMA:0517223651, GOC:tfm] +
"Circulating body substance which consists of blood plasma and hemoglobin-carrying red blood cells. Excludes blood analogues (see UBERON:0000179 haemolymphatic fluid)." [FMA:9670, Wikipedia:Blood] +
"Circulating fluid that is part of the hemolymphoid system. Blood, lymph, interstitial fluid or its analogs." [] +
"The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated." [GOC:tfm, ISBN:0412046911, MESH:A.11.436.348, PMID:19717280] +
"An animal cell that has characteristics of both a fibroblast cell and a smooth muscle cell." [GOC:dsd, GOC:tfm, MESH:D058628, PMID:19800625, PMID:20630469] +
"A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [MESH:A.11.620] +
"A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast)." [MESH:A.11.620.520, MESH:D032389, PMID:9315361] +
"A cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system." [MESH:A.08.800.550.700.500] +
"A mechanoreceptor cell located in the inner ear that is sensitive to auditory stimuli. The accessory sensory structures are arranged so that appropriate stimuli cause movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system." [MESH:A.08.663.650.250] +
"Dorsal part (roof region) of the telencephalon[GO]." [GO:0021543, https://sourceforge.net/tracker/?func +
"Dorsal part (base region) of the telencephalon." [GO:0021544, GO_REF:0000021, ISBN10:0471888893, PMID:12626695] +
"A cell whose function is determined by the generation or the reception of an electric signal." [FB:ma] +
"Nonparenchymatous organ that primarily consists of dense connective tissue aggregated into fasciculi by connective tissue. Examples: sutural ligament, radiate sternocostal ligament, ligament of liver, ovarian ligament[FMA]." [FMA:21496, Wikipedia:Ligament] +
"A cell within an epithelial cell sheet whose main function is to act as an internal or external covering for a tissue or an organism." [JB:jb] +
"A meso-epithelial cell that lies between the cartilaginous fibers in the synovial membrane of a joint and produces hyaluronic acid." [GOC:tfm, ISBN:0721662544, PMID:17942474] +
"A granulocyte that has the activation marker CD15. CD15 is a carbohydrate and is not currently represented in the OBO domain." [GOC:tfm] +
"A cell whose primary function is to prevent the transport of stuff across compartments." [JB:jb] +
"A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier." [MESH:A.05.360.444.849.789] +
"A neuroglial cell of the peripheral nervous system which forms the insulating myelin sheaths of peripheral axons." [GOC:cvs, GOC:tfm, MESH:A.08.637.800] +
"Any cell capable of ingesting particulate matter via phagocytosis." [GOC:add, ISBN:0721601464] +
"A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells." [GO_REF:0000031, GOC:add, GOC:tfm, http://www.clt.astate.edu/wwilliam/, PMID:16213494, PMID:1919437] +
"A lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity." [GO_REF:0000031, GOC:add, GOC:tfm, ISBN:0781735149] +
"A modified epidermal cell located in the stratum basale. They are found mostly in areas where sensory perception is acute. Merkel cells are closely associated with an expanded terminal bulb of an afferent myelinated nerve fiber." [MESH:A.08.800.550.700.500.425] +
"A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear." [MESH:A.08.637] +
"A cell characteristically found lining hollow organs that are subject to great mechanical change due to contraction and distention; originally thought to represent a transition between stratified squamous and columnar epithelium." [GOC:tfm, ISBN:0721662544] +
"A membrane building the amniotic sac that surrounds and protects an embryo. It is developed in reptiles, birds, and mammals, which are hence called 遯ｶ蟒｣mniota遯ｶ�; but not in amphibians and fish (Ichthyopsida), which are consequently termed 遯ｶ蟒｣namniota遯ｶ�. The primary function of this is the protection of the embryo for its development. It stems from parts of the mesoderm on the outer side and the ectoderm on the inner side[WP]." [Wikipedia:Amnion] +
"Organism at the blastula stage - an early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence." [Wikipedia:Blastula] +
"The breast is the upper ventral region of an animal's torso, particularly that of mammals, including human beings. The breasts of a female primate遯ｶ蜀ｱ body contain the mammary glands, which secrete milk used to feed infants. Both men and women develop breasts from the same embryological tissues. However, at puberty female sex hormones, mainly estrogens, promote breast development, which does not happen with men. As a result women's breasts become more prominent than men's. [WP,unvetted]." [Wikipedia:Breast] +
"An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell." [GOC:dsd, MESH:A.11.436.397, MESH:D015603, PMID:15582983, PMID:15749908, PMID:19727116] +
"Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid." [GOC:tfm, ISBN:0517223651, ISBN:0721662544] +
"A cell secreting sebun, an oily substance secreted by sebaceous glands, composed of keratin, fat, and cellular debris." [MESH:A.12.200.702] +
"An epithelial cell that lines the peripheral gas exchange region of the lungs of air-breathing vertebrates." [GOC:tfm, PMID:20054144] +
"A cell of the strip of specialized ectoderm flanking each side of the embryonal neural plate, which after the closure of the neural tube, forms a column of isolated cells along the dorsal aspect of the neural tube. Most of the cranial and all of the spinal sensory ganglion cells arise by differentiation of neural crest cells." [MESH:A.16.254.600] +
"A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors." [GOC:tfm, PMID:5025404] +
"A cell found within the adrenal medulla that secrete biogenic amine hormones upon stimulation." [GOC:tfm, http://www.britannica.com/EBchecked/topic/6405/adrenal-gland] +
"An early neural cell developing from the early ependymal cell of the neural tube." [GOC:tfm, ISBN:0618947256] +
"In anatomy, the throat is the anterior part of the neck, in front of the vertebral column. It consists of the pharynx and larynx. An important feature of the throat is the epiglottis, a flap which separates the esophagus from the trachea and prevents inhalation of food or drink. The throat contains various blood vessels, various pharyngeal muscles, the trachea (windpipe) and the esophagus. The hyoid bone and the clavicle are the only bones located in the throat of mammals. It is sometimes considered a synonym for fauces. [WP,unvetted]." [Wikipedia:Throat] +
"A lining of mostly endodermal origin, covered in epithelium, which is involved in absorption and secretion. They line various body cavities that are exposed to the external environment and internal organs. It is at several places continuous with skin: at the nostrils, the lips, the ears, the genital area, and the anus. The sticky, thick fluid secreted by the mucous membranes and gland is termed mucus. The term mucous membrane refers to where they are found in the body and not every mucous membrane secretes mucus[WP]" [Wikipedia:Mucous_membrane] +
"A specialized mesenchymal cell that resides in the dermal papilla located at the bottom of hair follicles. This cell plays a pivotal roles in hair formation, growth, and cycling." [GOC:tfm, PMID:9893172] +
"A set of midline structures surrounding the brainstem of the mammalian brain, originally described anatomically, e.g., hippocampal formation, amygdala, hypothalamus, cingulate cortex. Although the original designation was anatomical, the limbic system has come to be associated with the system in the brain subserving emotional functions. As such, it is very poorly defined and doesn't correspond closely to the anatomical meaning any longer. [BirnLex]. including the hippocampus, amygdala, anterior thalamic nuclei, and limbic cortex, which support a variety of functions including emotion, behavior, long term memory, and olfaction [Wikipedia]." [BIRNLEX:Limbic_system, Wikipedia:Limbic_system] +
"A cell lining the outside of the blastocyst. After binding to the endometrium, trophoblast cells develop into two distinct layers, an inner layer of mononuclear cytotrophoblast cells and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblast cells, which form the early fetal-maternal interface." [GOC:tfm, MESH:A.11.936] +
"functional part of an organ in the body. This is in contrast to the stroma, which refers to the structural tissue of organs, being exactly, connective tissues. Early in development the mammalian embryo has three distinct layers: ectoderm (external layer), endoderm (internal layer) and in between those two layers the middle layer or mesoderm. The parenchyma of most organs is of ectodermal (brain, skin) or endodermal origin (lungs, gastrointestinal tract, liver, pancreas). The parenchyma of a few organs (spleen, kidneys, heart) is of mesodermal origin. The stroma of all organs is of mesodermal origin[WP]." [Wikipedia:Parenchyma] +
"A multifate stem cell found in skeletal muscle than can differentiate into many different cell types. Distinct cell type from satellite cell." [PMID:18282570] +
"The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm[GO]." [GO:0001824, Wikipedia:Blastocyst] +
"An epithelial cell of the integument (the outer layer of an organism)." [Flybase:dsj, MA:ma] +
"The urothelium is the epithelial tissue layer that lines much of the urinary tract, including the renal pelvis, the ureters, the bladder, and parts of the urethra." [Wikipedia:Urothelium] +
"The corpus striatum (striated body) is a compound structure consisting of the caudate nucleus and the lentiform nucleus, which consists of the putamen and the globus pallidus[WP]." [Wikipedia:Corpus_striatum] +
"In humans the thigh is the area between the pelvis and the knee. Anatomically, it is part of the lower limb. The single bone in the thigh is called the femur. This bone is very thick and strong (due to the high proportion of cortical bone), and forms a ball and socket joint at the hip, and a condylar joint at the knee. [WP,unvetted]." [Wikipedia:Thigh] +
"Anatomical system that consists of all the muscles of the body[VSAO, modified]." [VSAO:0000033] +
"group of nerve cells that serve the sense of hearing by sending a representation of sound from the cochlea to the brain. The cell bodies of the spiral ganglion neurons are found in the spiral structure of the cochlea[WP]. the group of nerve cell bodies that conveys auditory sensation from the organ of Corti to the hindbrain and resides on the cochlear part of the vestibulocochlear nerve (eighth cranial nerve)[MP]." [MP:0002855, Wikipedia:Spiral_ganglion] +
"Any one of the largest papilla of the tongue, 8 to 12 in number, arranged in the form of a V anterior to the sulcus terminalis of the tongue" [BTO:0001705, Wikipedia:Vallate_papilla] +
"A cell that initiates an electrical signal and passes that signal to another cell." [FB:ma] +
"Area of the occipital lobe concerned with vision." [MESH:A.08.186.211.730.885.213.571.735] +
"small, nipple-like extensions (or interdigitations) of the dermis into the epidermis. They can be observed at the surface of the skin in hands and feet as epidermal or papillary ridges (colloquially known as fingerprints). The dermal papillae nourishes all hair follicles and bring food and oxygen to the lower layers of epidermal cells. The pattern of ridges they produce in hands and feet are inherited features that are developed before birth. They remain unaltered (except size) throughout life, and are therefore used for fingerprints. The dermal papillae are part of the uppermost layer of the dermis, the papillary dermis, and the ridges they form greatly increase the surface area between the dermis and epidermis. Because the dermis' main function is to support the epidermis, this greatly increases the exchange of oxygen, nutrients, and waste products between these two layers. Additionally, the increase in surface area prevent the dermal and epidermal layers from separating from each others by strengthening the junction between them. With age, the papillae tend to flatten and sometimes increase in numbers. Dermal papillae also play a pivotal role in hair formation, growth and, cycling" [Wikipedia:Dermal_papillae] +
"A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative)." [GOC:add, ISBN:0781735149] +
"Langerhans cell is a conventional dendritic cell that has plasma membrane part CD207. A Langerhans cell is a stellate dendritic cell of myeloid origin, that appears clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus." [GO_REF:0000031, GOC:add, GOC:amm, ISBN:0721601464, ISBN:0781735149, PMCID:PMC2346585, PMID:17850486] +
"Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body." [CARO:MAH] +
"Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures." [CARO:MAH] +
"Anatomical group that is has as its parts distinct anatomical structures interconnected by anatomical structures at a lower level of granularity[CARO]. A group of organs that work together to perform a certain task [Wikipedia]." [CARO:0000011, CARO:MAH, Wikipedia:Organ_system] +
"Anatomical structure that is an individual member of a species and consists of more than one cell." [CARO:0000012, CARO:MAH, Wikipedia:Multi-cellular_organism] +
