Personal tools

Coexpression cluster:C3582

From FANTOM5_SSTAR

Jump to: navigation, search


Full id: C3582_neuroblastoma_neuroectodermal_cerebellum_merkel_argyrophil_duodenum_pineal



Phase1 CAGE Peaks

  Short description
Hg19::chr16:67197586..67197607,+ p5@FBXL8
Hg19::chr16:67197614..67197625,+ p10@HSF4
Hg19::chr16:67197654..67197716,+ p3@HSF4


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


No GOStat results

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset


uberon_data


Uber Anatomy
Ontology termp-valuen
adult organism3.90e-42114
regional part of nervous system1.60e-3953
regional part of brain1.60e-3953
neural tube7.79e-3956
neural rod7.79e-3956
future spinal cord7.79e-3956
neural keel7.79e-3956
nervous system7.52e-3689
central nervous system2.28e-3481
brain1.32e-3268
future brain1.32e-3268
regional part of forebrain4.23e-3141
forebrain4.23e-3141
anterior neural tube4.23e-3141
future forebrain4.23e-3141
neurectoderm1.59e-2886
neural plate1.10e-2782
presumptive neural plate1.10e-2782
brain grey matter4.80e-2534
gray matter4.80e-2534
telencephalon1.17e-2434
ecto-epithelium2.66e-23104
regional part of telencephalon1.81e-2232
cerebral hemisphere3.27e-2232
ectoderm-derived structure5.94e-22171
ectoderm5.94e-22171
presumptive ectoderm5.94e-22171
pre-chordal neural plate2.55e-2061
regional part of cerebral cortex3.14e-1922
neocortex3.19e-1920
structure with developmental contribution from neural crest1.93e-16132
cerebral cortex2.62e-1625
pallium2.62e-1625
organ system subdivision8.75e-16223
neural nucleus1.42e-109
nucleus of brain1.42e-109
basal ganglion2.80e-109
nuclear complex of neuraxis2.80e-109
aggregate regional part of brain2.80e-109
collection of basal ganglia2.80e-109
cerebral subcortex2.80e-109
segmental subdivision of hindbrain1.76e-0912
hindbrain1.76e-0912
presumptive hindbrain1.76e-0912
posterior neural tube6.63e-0915
chordal neural plate6.63e-0915
brainstem7.68e-096
segmental subdivision of nervous system1.41e-0813
tube1.47e-08192
anatomical conduit3.51e-08240
diencephalon6.17e-087
future diencephalon6.17e-087
telencephalic nucleus7.43e-087
parietal lobe1.29e-075
temporal lobe2.23e-076
organ part2.41e-07218
gland of diencephalon2.82e-074
neuroendocrine gland2.82e-074
anatomical cluster3.62e-07373


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.708947
MA0004.10.826076
MA0006.11.5435
MA0007.10.804807
MA0009.11.3275
MA0014.10.118426
MA0017.10.686276
MA0019.10.990656
MA0024.11.21731
MA0025.11.46617
MA0027.12.95767
MA0028.10.658629
MA0029.11.23771
MA0030.11.22561
MA0031.11.15713
MA0038.10.94098
MA0040.11.24388
MA0041.10.847069
MA0042.10.810843
MA0043.11.32783
MA0046.11.31611
MA0048.12.45333
MA0050.10.81185
MA0051.10.936307
MA0052.11.24796
MA0055.10.190716
MA0056.10
MA0057.10.333427
MA0058.10.716037
MA0059.10.714521
MA0060.10.492218
MA0061.10.456531
MA0063.10
MA0066.10.941452
MA0067.11.65513
MA0068.10.405474
MA0069.11.31207
MA0070.11.30033
MA0071.10.897953
MA0072.11.29561
MA0073.10.0185922
MA0074.10.935474
MA0076.10.734647
MA0077.11.28751
MA0078.11.04495
MA0081.10.714712
MA0083.11.33535
MA0084.11.84562
MA0087.11.29304
MA0088.10.257905
MA0089.10
MA0090.10.751469
MA0091.10.829044
MA0092.10.785956
MA0093.10.642957
MA0095.10
MA0098.10
MA0100.10.956299
MA0101.10.646932
MA0103.10.628063
MA0105.10.31555
MA0106.10.986396
MA0107.10.556367
MA0108.21.15387
MA0109.10
MA0111.11.80901
MA0113.11.00436
MA0114.10.549955
MA0115.11.57693
MA0116.12.36034
MA0117.11.36676
MA0119.10.695578
MA0122.11.39371
MA0124.11.53432
MA0125.11.44766
MA0130.10
MA0131.11.06461
MA0132.10
MA0133.10
MA0135.11.35921
MA0136.10.948776
MA0139.10.440097
MA0140.10.894983
MA0141.10.712476
MA0142.11.12317
MA0143.11.00455
MA0144.10.531867
MA0145.10.273764
MA0146.10.107247
MA0147.10.565108
MA0148.10.854239
MA0149.10.884158
MA0062.20.449458
MA0035.20.894194
MA0039.20.0526989
MA0138.21.04628
MA0002.20.476938
MA0137.20.666381
MA0104.20.491226
MA0047.20.973066
MA0112.20.264678
MA0065.20.277623
MA0150.10.744617
MA0151.10
MA0152.10.902317
MA0153.11.43021
MA0154.10.838867
MA0155.10.256269
MA0156.10.669101
MA0157.11.09377
MA0158.10
MA0159.11.38935
MA0160.10.871361
MA0161.10
MA0162.10.149099
MA0163.10.122425
MA0164.11.01792
MA0080.20.643061
MA0018.20.987913
MA0099.20.902716
MA0079.20.0373086
MA0102.21.88331
MA0258.10.519674
MA0259.10.575594
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
CHD2#1106310.34402283411690.0009033701102746880.00659677464319523
EBF1#187938.9064668465690.00141523283560980.00914185441107449
ELF1#199734.258097958807540.01295179875054610.0461489853539041
NRF1#4899312.21027944771090.0005492172401020010.00470662996135332
PAX5#507936.669565531177830.003370290999677260.0172704882839553
SMARCB1#6598318.25271578115740.000164397760679890.00202853706612087
SUZ12#23512350.11578091106297.93834897779404e-060.000221914675827578



Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.