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Coexpression cluster:C1539

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Full id: C1539_carcinoid_cerebellum_temporal_neuroectodermal_occipital_insula_postcentral



Phase1 CAGE Peaks

Hg19::chr7:70596291..70596318,+p@chr7:70596291..70596318
+
Hg19::chr7:70596521..70596558,+p@chr7:70596521..70596558
+
Hg19::chr7:70596628..70596711,+p1@WBSCR17
Hg19::chr7:70596874..70596898,+p3@WBSCR17
Hg19::chr7:70596902..70596919,+p4@WBSCR17
Hg19::chr7:70597109..70597144,+p2@WBSCR17


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
neuronal stem cell8.71e-098
neural cell4.34e-0825
neuron2.06e-076
neuroblast2.06e-076
electrically signaling cell2.06e-076
Uber Anatomy
Ontology termp-valuen
adult organism9.42e-59114
central nervous system5.85e-5681
nervous system3.01e-5489
neural tube1.61e-5356
neural rod1.61e-5356
future spinal cord1.61e-5356
neural keel1.61e-5356
regional part of nervous system5.96e-5353
regional part of brain5.96e-5353
neurectoderm1.18e-4586
brain1.76e-4568
future brain1.76e-4568
neural plate1.32e-4382
presumptive neural plate1.32e-4382
regional part of forebrain2.02e-4041
forebrain2.02e-4041
anterior neural tube2.02e-4041
future forebrain2.02e-4041
telencephalon6.55e-3934
brain grey matter1.05e-3834
gray matter1.05e-3834
cerebral hemisphere7.78e-3832
regional part of telencephalon4.89e-3732
ectoderm-derived structure1.43e-32171
ectoderm1.43e-32171
presumptive ectoderm1.43e-32171
pre-chordal neural plate1.65e-3261
ecto-epithelium6.31e-32104
cerebral cortex7.74e-3125
pallium7.74e-3125
regional part of cerebral cortex8.81e-2822
structure with developmental contribution from neural crest1.42e-27132
organ system subdivision2.56e-27223
neocortex2.11e-2520
posterior neural tube8.81e-1415
chordal neural plate8.81e-1415
anatomical cluster9.53e-14373
segmental subdivision of hindbrain2.37e-1312
hindbrain2.37e-1312
presumptive hindbrain2.37e-1312
segmental subdivision of nervous system4.99e-1213
multi-cellular organism8.29e-12656
organ part1.04e-10218
regional part of metencephalon2.25e-109
metencephalon2.25e-109
future metencephalon2.25e-109
multi-tissue structure2.60e-10342
basal ganglion4.32e-109
nuclear complex of neuraxis4.32e-109
aggregate regional part of brain4.32e-109
collection of basal ganglia4.32e-109
cerebral subcortex4.32e-109
tube1.09e-09192
neural nucleus2.61e-099
nucleus of brain2.61e-099
embryo2.80e-09592
temporal lobe3.22e-096
gyrus1.12e-086
organ8.84e-08503
anatomical conduit9.81e-08240
cerebellum1.08e-076
rhombic lip1.08e-076
telencephalic nucleus1.09e-077
limbic system1.26e-075
occipital lobe1.67e-075
anatomical system2.35e-07624
embryonic structure2.40e-07564
brainstem2.75e-076
germ layer2.78e-07560
germ layer / neural crest2.78e-07560
embryonic tissue2.78e-07560
presumptive structure2.78e-07560
germ layer / neural crest derived structure2.78e-07560
epiblast (generic)2.78e-07560
anatomical group2.79e-07625
parietal lobe3.14e-075
developing anatomical structure4.47e-07581


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.15.21839
MA0004.10.558729
MA0006.11.01439
MA0007.10.539222
MA0009.11.03681
MA0014.13.70108
MA0017.10.432438
MA0019.10.7124
MA0024.10.929647
MA0025.11.17262
MA0027.12.65688
MA0028.11.05129
MA0029.10.949428
MA0030.10.937696
MA0031.10.871496
MA0038.10.665566
MA0040.10.955415
MA0041.10.578072
MA0042.10.544748
MA0043.11.03713
MA0046.11.02569
MA0048.11.45353
MA0050.10.545671
MA0051.10.661179
MA0052.10.959373
MA0055.10.213007
MA0056.10
MA0057.10.450439
MA0058.10.458909
MA0059.10.457555
MA0060.10.267412
MA0061.10.23892
MA0063.10
MA0066.11.59928
MA0067.11.35893
MA0068.11.09642
MA0069.11.02175
MA0070.11.01032
MA0071.10.625297
MA0072.11.00572
MA0073.10.0214749
MA0074.10.660398
MA0076.10.475586
MA0077.10.997832
MA0078.10.763954
MA0081.10.457725
MA0083.11.04447
MA0084.11.5477
MA0087.11.00322
MA0088.13.57211
MA0089.10
MA0090.10.490736
MA0091.10.561458
MA0092.10.522012
MA0093.10.394379
MA0095.10
MA0098.10
MA0100.10.679972
MA0101.10.397846
MA0103.10.381434
MA0105.10.419295
MA0106.11.68738
MA0107.10.320267
MA0108.20.868347
MA0109.10
MA0111.11.25994
MA0113.10.725375
MA0114.10.314898
MA0115.11.28169
MA0116.10.323925
MA0117.11.07516
MA0119.10.440684
MA0122.11.10154
MA0124.11.23968
MA0125.11.15445
MA0130.10
MA0131.10.782708
MA0132.10
MA0133.10
MA0135.11.06778
MA0136.10.672893
MA0139.12.62599
MA0140.10.622527
MA0141.10.455728
MA0142.10.838805
MA0143.10.725558
MA0144.10.299851
MA0145.10.707171
MA0146.11.8938
MA0147.10.87383
MA0148.10.584698
MA0149.10.612449
MA0062.20.658749
MA0035.20.621793
MA0039.21.86512
MA0138.20.765223
MA0002.20.255126
MA0137.20.414885
MA0104.21.35181
MA0047.20.695777
MA0112.21.65732
MA0065.20.109623
MA0150.11.21643
MA0151.10
MA0152.10.629368
MA0153.11.13732
MA0154.10.132326
MA0155.11.09123
MA0156.10.417278
MA0157.10.810597
MA0158.10
MA0159.10.328286
MA0160.10.600559
MA0161.10
MA0162.11.87239
MA0163.12.60605
MA0164.10.738243
MA0080.20.394469
MA0018.20.709805
MA0099.20.629739
MA0079.23.22572
MA0102.21.58513
MA0258.10.289793
MA0259.10.336472
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.